<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00957

Description Uncharacterized protein
SequenceMAPEVYGHIVKGYHDVFPYAQFHWVRHLLACLELENSAGAQPQVMSKLIDLLLRFSQHLSQQASCHDTSQENKPICLQGDADAITIPLSRLPTVVQRYLLFGSGVKNKDMPSTTDKYDRENTVSDPTILTEAFSCFQNDFENLLRGSNELQCQEIGITPADLDSFRFRHSNAPYLCRHSRCARTTFGFDTVNELKQHESTHMPKFHCMETNCEERFTTRRALQIHTRKCHAGIEHIILPLFLASDEPAGPKRLPAITQEVAGLLIRPGSEPFPSFEGMAFSHPSVQQNSNISIGERAAQISSLAETLRLVRPPVEFRRAVEVSQQFERKCFTQSGSREDYIRECSEKLGRIRDQRAQQMGQGNPDAMQAMGMQGMQIPSQNFPQMQQMGQNMNTNMSLRRQQQQQQQQQQQQQQWQQQQRQQTTPQHIMSLPQNAEGQVAMIQGNENQQKQNQFPELSPEDNKAINLRAAELAKNISKEEMRSIVAKMDPQLRQNLARKAVDPIIYHFWRLATKEFRQRRKEMEGGLSGAGKAGIEPRLGEYKLVINSSRALRRSPFPQPKRQPVKFSSGRI
Length572
PositionTail
OrganismExophiala aquamarina CBS 119918
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Exophiala.
Aromaticity0.07
Grand average of hydropathy-0.717
Instability index67.54
Isoelectric point9.00
Molecular weight65321.34
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00957
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.28|      24|      28|     357|     384|       1
---------------------------------------------------------------------------
  357-  384 (42.92/29.91)	QQMGQG.NPDamqaMGMQGMQIPSQNFPQ
  386-  410 (39.36/19.31)	QQMGQNmNTN....MSLRRQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.54|      46|      69|     446|     494|       2
---------------------------------------------------------------------------
  446-  494 (68.12/52.99)	ENQQKQNQFP.ELSPEDNKAINLRAAE..LAKNISKEEMRSIVAKmdPQlRQ
  515-  563 (70.41/43.77)	EFRQRRKEMEgGLSGAGKAGIEPRLGEykLVINSSRALRRSPFPQ..PK.RQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     136.57|      47|      69|      59|     125|       3
---------------------------------------------------------------------------
   59-  111 (68.62/54.27)	LSQQASCHDTSQENkPICLQGDADAitIPlSRLPTVVQRY..LLFGSGvkNKDMP
  129-  149 (22.69/22.10)	LTEAFSCFQNDFEN...LLRGSNE...............................
  239-  273 (45.25/20.66)	...............PLFLASDEPA..GP.KRLPAITQEVagLLIRPG..SEPFP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00957 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IRECSEKLGRIRDQRAQQMGQGNPDAMQAMGMQGMQIPSQNFPQMQQMGQNMNTNMSLRRQQQQQQQQQQQQQQWQQQQRQQTTPQHIMSLPQNAEGQVAMIQGNENQQKQNQFPELSPEDNKAINLRAAELA
341
473










Molecular Recognition Features






MoRF SequenceStartStop




1) KRQPVKFSSGRI
2) VINSSRALRRS
561
545
572
555