Description | Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MVVTCLVRWKNATGMRDFTYIQEHVTKSLHGKNTGPWSLGFKVYRDVNHGSGGRSNPSSSLSSAMHHQQSSQGKDNKLMYQVTLGQQPGQVYCMVDGSVVVEAEKELEIILSRLKNLWQMRQSVVIEGTSFEIGDFTLRVANILLGSTYKGLLLEISYHPCSAPNVAADLFREFVESVVHPTAQLSCEYEYNYENVGLSNQDFTSAHTGYQYMMLFRNDGLL |
Length | 222 |
Position | Head |
Organism | Lichtheimia corymbifera JMRC:FSU:9682 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Lichtheimiaceae> Lichtheimia. |
Aromaticity | 0.10 |
Grand average of hydropathy | -0.266 |
Instability index | 37.87 |
Isoelectric point | 6.23 |
Molecular weight | 24943.96 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP00885 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) KLMYQ 2) SLGFKVYR | 77 38 | 81 45 |
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