<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00866

Description Uncharacterized protein
SequenceMAGRHQAQFTRYASMNASYPNVGPTNGGNPHGNSGNNLGVPFPTPNGGGPAQSSSQNLSAASVSSTGMAGGSIYHTTTPTMTSPYSTSSSPGYHSPNFQRYGTHQHHRHRHSNNLQLRKYTLTPPTPQPLSKSMKSLGYPGMYYQRPDQDEDIMTESNVRNGFIDRPAVSNEHTCAHDMVYSKLQDDQRILGELGAFAVDVLKRKQNAARITGPSTFRPPMRSTLIEPKKEQWMQDLANSTIPLRKLARNVPHGFKNEKLLETLAAKQVPFLRATWYIKVVGLSEMQSQRNTNNNGDDPHQKAWTKVVTGHLQKQLKELSPPQSSTSSSSVTTGRGYKIYPSTPNSHENMSRTWSSPESRAQFEQRWAYTTQLTKWQYCEGLLDQRYFLKWTLDVLSKHHSFEVIWLMLTYVVQDYLDEYRTNRALMLMLIKPLVKTYHALTQVLGQVTNEGLLWVYGEIKKHIERLLQSLFLSTPDVFVIPKLYHQYRHVFDTIFGEETLKDPSVALPDICHVMQRYWTMVKARNEVFCGTLEENQLLSDSSKAMLQAVDTTSDTTSDDAPRQGQMTEDQVIRILDSIGRNVDSGTGLMINENGWVDLRGQTATTASHAIFGSTKGAIDSIQQHVSVMCRWATSDSRHGHWRPYLVASILLRWRDQNATLRNSTLQDALIKWLDAEMDAGHGQDTNDMVDVDMTADQVVDEPKPAVILLFDTLIRMQLFSFQKFLLRLIARGDLEPKKRDQPRTRCCLNYLAAFPLTPAPSSLVNQRRIALYGTRNGQASQVEDDTLFQLKRLAKLAVAASPEDAENDNDINSLFGKDATNLTQPTTDDSIQSYELSLSNALESELLPILRNATRYIVLSFTSDWLIPEVKRFVVKSVPIGEDNWRVMTSPGSCLLNTRQYVTIIKILEYAQDYLNVIDLALWMLDKSNERALYSFAIDTLRKHASVWKLLNYGQRIADAIWEKHQNLQSQSVRERCLMMYMIQLVQEGYWISDEKRAQLQRDLHFKPKRTQYMGRNSTSLSTELNQLIRNPTMSSVQNAVDAVGGGHNAGAVNNFLQSVFTTAFDTLHQYAKENRITSLSVDQREPIYEFRRRVCSMVDFIKAVAEQTTLTGQLDQVVIQWLQQHCSPSSATKLDDLYEQHTWLPLFFALLVTRRLISIDLILKHFCLPWLNTIGIEAQQRCESQWTETTTETQPLRQLCKNIVILVRMLVVQENPELNPIMEENQDVPDSLWVLRAEEIFQLQVQRQPQLATNLDKLDNMFGLVHSTITIVSNLPFSSLLIQDLVRLRTDLLQLDWFRRACTRDVNSIYQHFTTTGATPASTSIDGGDEIRKKMLSIVDELIGGNMNLVNEAPDNMVPTSNDMEPNFGERLQAVFANLSQWNEEQCRVQLNLLLDNIMLPPSSSTRQTSQNENGTSGAGGDDATAATAAATSANVNATGSDNVVPNNPATMDMDSSPAPTASIDSNKDLDLFVRFYFDAVLFSANDNEITTNAHQRRFEFLRNLIQGLRKPVLLALLDHGIRMLEGHGAEELGFPYTILLKSHNSHPDQDNAPCFYSGEQYAQQCQAFFQIMQHLLAKDVWTDTQKIALVKALFRQVEQFRNAMAVYIVMESTDHVSFAEASRAIQLTKSLDLAVTMLKTEGLPEDEAQNGPRVMIEDIRISLLLRLRLLVPFASLIWEHPNADQCNILEWLRLLVSLLGNAIVHGNGSQERIFEFVLDLVSLLIDADIDLDLKKTCLGHLSSMHGELSGLPAMFHSRVKRILPYLAHNIYLSNTRLASSILGAPNTTDPQQQQQHVEGCMNTSRPWEWLEDYANEPPHVNDAPISLALFHGCKAKKSENTYVRWYHFGFDDGLTTIADEDDDTTAVHVGMVGSSHRMGRRKKQLPQSTDAAPMDTSTTTTNTTNTMYTEDNQQHPLAKRRISEMEDGELP
Length1934
PositionKinase
OrganismLichtheimia corymbifera JMRC:FSU:9682
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Lichtheimiaceae> Lichtheimia.
Aromaticity0.08
Grand average of hydropathy-0.401
Instability index41.53
Isoelectric point5.99
Molecular weight218515.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00866
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.02|      37|      42|     900|     940|       1
---------------------------------------------------------------------------
  900-  940 (54.88/46.37)	RQYVTIIKILEYAQdylNVIDlALW.....MLDKS.NERALYSFAID
  943-  985 (59.14/36.63)	RKHASVWKLLNYGQ...RIAD.AIWekhqnLQSQSvRERCLMMYMIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.46|      17|      19|      85|     101|       2
---------------------------------------------------------------------------
   85-   99 (24.59/15.07)	...........YSTS.SSPGYHSPNFQ
  100-  116 (23.66/14.16)	RY.......gtHQHH.RHR..HSNNLQ
  119-  145 (18.21/ 8.83)	KYtltpptpqpLSKSmKSLGYPGMYYQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.19|      42|      42|     745|     786|       3
---------------------------------------------------------------------------
  745-  786 (73.83/47.47)	TRCCLNYLAAFPLTPAPSSLVNQRRI.ALYGTRNGQASQ.VEDD
  787-  830 (59.36/36.64)	TLFQLKRLAKLAVAASPEDAENDNDInSLFGKDATNLTQpTTDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.02|      14|      16|     653|     668|       4
---------------------------------------------------------------------------
  653-  668 (20.81/18.39)	RWRDqnATLRNSTLQD
  672-  685 (27.20/16.44)	KWLD..AEMDAGHGQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.10|      15|      42|      14|      28|       5
---------------------------------------------------------------------------
   14-   28 (29.55/19.46)	SMNASYPNVGPTN..GG
   37-   48 (22.20/12.44)	NLGVPFP...TPN..GG
   55-   71 (19.35/ 9.73)	SQNLSAASVSSTGmaGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.40|      18|      46|    1171|    1188|       6
---------------------------------------------------------------------------
 1171- 1188 (36.86/25.33)	PWLNTIGIEAQQRCESQW
 1218- 1235 (35.54/24.12)	PELNPIMEENQDVPDSLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.42|      36|     123|    1124|    1159|       7
---------------------------------------------------------------------------
 1124- 1159 (65.45/50.13)	LQQHCSPSSAT...KLDDLYEQ.HTWLP....LFFALLVTRRLI
 1245- 1288 (46.97/33.30)	LQVQRQPQLATnldKLDNMFGLvHSTITivsnLPFSSLLIQDLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     188.38|      58|     459|     534|     625|       8
---------------------------------------------------------------------------
  547-  610 (93.04/85.77)	LQAVDTTSDTTSDDAPR.QGQMTEDQVIRILDSIGRNVDSgtglmiNENGWVDLRGQTATTASHA
 1374- 1432 (95.35/36.93)	LQAVFANLSQWNEEQCRvQLNLLLDNIMLPPSSSTRQTSQ......NENGTSGAGGDDATAATAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.68|      22|      25|     220|     244|       9
---------------------------------------------------------------------------
  220-  244 (35.55/28.50)	PMRSTlieP...KKEQWMQDLANSTIPL
  247-  271 (30.14/16.31)	LARNV...PhgfKNEKLLETLAAKQVPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.90|      21|      21|     396|     416|      10
---------------------------------------------------------------------------
  396-  416 (38.08/28.31)	LSKHHSFEVIWLML.TYVVQDY
  417-  438 (30.82/21.31)	LDEYRTNRALMLMLiKPLVKTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.28|      10|     548|    1161|    1170|      11
---------------------------------------------------------------------------
 1161- 1170 (20.14/15.43)	IDLILKHFCL
 1732- 1741 (19.14/14.24)	IDLDLKKTCL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00866 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DEDDDTTAVHVGMVGSSHRMGRRKKQLPQSTDAAPMDTSTTTTNTTNTMYTEDNQQHPLAKRRISEMEDGELP
2) LPPSSSTRQTSQNENGTSGAGGDDATAATAAATSANVNATGSDNVVPNNPATMDMDSSPAPTA
3) MAGRHQAQFTRYASMNASYPNVGPTNGGNPHGNSGNNLGVPFPTPNGGGPAQSSSQNLSAASVSSTGMAGGSIYHTTTPTMTSPYSTSSSPGYHSPNFQRYGTHQHHRHRHSNNLQLRKYTLTPPTPQPLSKSMKSLGYPGMYYQRPDQDEDIMTESNVRNGFIDRPA
1862
1402
1
1934
1464
168










Molecular Recognition Features






MoRF SequenceStartStop




1) HPLAKRRISE
1918
1927