<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00837

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMAGPQHSFPSGFSNAQQGAMRNQFGGTPQIGGLMSSAQQTGLVNQQPYGVGIQASTQQALSQQQQNQQLQMQQQQIQQQLQQQQMQQLQQQQQQQQAANQNNTQQQQGNQPQQNPSQQQPPNKEFNTASLCRFGQETVQDIVSRTQEVFQALKAIQPPNGTAQGANTSNEKKSKVHEQLKTIRILFKRLRLIYEKCNENCQGMEYTHIESLIPLKEEWDMKSDEKKTSESYRLVCEENKEIMEQVILKNRHLKEIIDHLRRIIWEINTMLTMRRS
Length275
PositionHead
OrganismZootermopsis nevadensis (Dampwood termite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Termopsidae> Zootermopsis.
Aromaticity0.05
Grand average of hydropathy-1.037
Instability index61.13
Isoelectric point8.87
Molecular weight31660.14
Publications
PubMed=24845553

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00837
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.65|      26|      26|      77|     102|       1
---------------------------------------------------------------------------
   78-  102 (43.93/13.14)	.QQLQQ..........QQMQQLQQQQQQQQAANQN.N
  103-  126 (37.27/10.01)	TQQ..Q..........QG.NQPQQNPSQQQPPNKEfN
  134-  169 (29.44/ 6.34)	GQETVQdivsrtqevfQALKAIQPPNGTAQGANTS.N
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.11|      14|      16|      32|      46|       2
---------------------------------------------------------------------------
   32-   46 (19.99/13.85)	GLMSSAQQTgLVNQQ
   51-   64 (23.12/10.71)	GIQASTQQA.LSQQQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00837 with Med30 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LQQQQMQQLQQQQQQQQAANQNNTQQQQGNQPQQNPSQQQPPNKEFNTASL
2) MAGPQHSFPSGFSNAQQGAMRNQFGGTPQIGGLMSSAQQTGLVNQQPY
80
1
130
48

Molecular Recognition Features

MoRF SequenceStartStop
NANANA