<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00825

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMAATTNGNGNLVDEFEEAFQSCLTVLTKEEALPTMEKDEIRVEVDHTILRFIDLARQMEAFFLQKRFLLSALKPELVVKEDTYELRLELVRKEELIKRHYEKIAVWQNLLADLQGWAKSPAQGPAPSGLPNGNAGPQPPAPPTGAPPQPNLPSNIQQQLQQQQLQQQQIQQQQMQQMQQQQMQQQIQQQQMQQQGPPGISVASGSGGPGPMVSPQQAMFMQQSAGPRGPPGFPTQGPGGVLQGPLAFLEKTTSNIGMPEGRR
Length262
PositionHead
OrganismZootermopsis nevadensis (Dampwood termite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Termopsidae> Zootermopsis.
Aromaticity0.05
Grand average of hydropathy-0.640
Instability index70.44
Isoelectric point5.33
Molecular weight28918.54
Publications
PubMed=24845553

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00825
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.76|      30|      31|     181|     211|       2
---------------------------------------------------------------------------
  181-  211 (55.41/23.78)	QMQQQI.QQQQMQQQGPPGISvASGSGG..PGPM
  213-  245 (48.36/17.24)	SPQQAMfMQQSAGPRGPPGFP.TQGPGGvlQGPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.74|      17|      19|     120|     137|       3
---------------------------------------------------------------------------
  120-  137 (29.47/14.18)	PAQGPAP.SGLPNgNAGPQ
  141-  158 (30.27/10.89)	PPTGAPPqPNLPS.NIQQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00825 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) WAKSPAQGPAPSGLPNGNAGPQPPAPPTGAPPQPNLPSNIQQQLQQQQLQQQQIQQQQMQQMQQQQMQQQIQQQQMQQQGPPGISVASGSGGPGPMVSPQQAMFMQQSAGPRGPPGFPTQGPGGVLQGPLAFLEKTTSNIGMPEGRR
116
262










Molecular Recognition Features






MoRF SequenceStartStop




1) LAFLEK
245
250