<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00822

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRYSKGKDDRFSVIVTSYSEGLGSCREFILRSQNSTIVHVRHKCWWLYVGCGAVQSETQYGLMQHSPSEIKEKLLKALDKEYNVVDMATVVEIIAILERTVITKEALETTRLGKYVNELRRKTTNELLARRAKDLVRRWRVMIQENNTAGVSTVCSHIPSAVHQTNGTNLLLHQVSPGLRSNVSPALPQFGSTAGRCYSPSSAAAGDATTNFIPGYPRSPVKPFVTGDLFLNPSHHFKESSSISRSISSPKLHPLAPQVKLPNVSSNSDHLGYHCRPSILVNMDSVPRTHASNKRLRKEPSQDVSAKKFSRPNGQVVKGFDFMKSCVPSQSEIHGDGSRDSISGMSQGSSSCEVIPLHNKVPVMDMVFGMTCAAVTTATTTATTTTMATTVTSTAATDPFTWSSICSTSVVTDTTSTHSTSATNIFVGTTVVTTAVSSATDTITGCSTTPVPPAKTRRKRTTKLRRVSASASVTQAISVGDILKEKIASKVRTPKVKTTQELVASVQAKTGGASGTLPEDKLGNLNVLLSENKPSLAKCILMSRGTPTDALEISRNKTEHIAKFLQSQSELHPIQEDPSIVPLAEMEDLRLQKHLRGLPGSSGGDNYNSSPAEVSSFSKLSKDILQQFSSSKDSQSASGIVTNIHDQTVEDILPPVDVDAICWDESVTDGTDSEPPVAKEVTEEVIRKFHTEHIENVNGNVNEGASCDDSDNFREWHETVSKRSYQGEFLHILPYVVID
Length739
PositionUnknown
OrganismZootermopsis nevadensis (Dampwood termite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Termopsidae> Zootermopsis.
Aromaticity0.05
Grand average of hydropathy-0.357
Instability index55.74
Isoelectric point8.27
Molecular weight80359.71
Publications
PubMed=24845553

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00822
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.85|      39|      39|     377|     415|       1
---------------------------------------------------------------------------
  377-  415 (70.83/49.89)	TATTTATTTTMATTVTSTA...ATDPFTWSSICSTSVVTDTT
  417-  451 (46.37/29.75)	THSTSATNIFVGTTVVTTAvssATDTITG...CSTTPV....
  655-  671 (18.65/ 6.92)	.........................PVDVDAICWDESVTDGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.57|      21|     250|      15|      35|       2
---------------------------------------------------------------------------
   15-   35 (38.63/29.60)	VTSYSEGLG.SCREFILRSQNS
  264-  285 (35.94/26.96)	VSSNSDHLGyHCRPSILVNMDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.09|      52|     140|     174|     227|       3
---------------------------------------------------------------------------
  174-  227 (84.51/52.58)	QVSPG...LRSNVsPALPQFGSTAGRcYSPSSAAAGDATTNFIPGYPRSPVKPFVTG
  315-  369 (84.57/44.18)	QVVKGfdfMKSCV.PSQSEIHGDGSR.DSISGMSQGSSSCEVIPLHNKVPVMDMVFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.70|      38|     374|      88|     133|       4
---------------------------------------------------------------------------
   88-  133 (49.60/52.16)	ATVVEIIAILErtvITKEalettRLGKYVNELRRKTTNELLAR.RAK
  471-  509 (56.10/37.87)	ASVTQAISVGD...ILKE.....KIASKVRTPKVKTTQELVASvQAK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00822 with Med26 domain of Kingdom Metazoa
Unable to open file!