<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00725

Description Uncharacterized protein
SequenceMTKLQRSTQLTPYKLKCDKESLNSRLGPPDFHPQTPNCPEETLTREYVQNGYKETVEGLEEVREISLTQAQTFNKPVVLKCREAIRKCLRAINESRAQKRKAGQVYGVPLSDSLLTKPGVFPEQRPCGEEFRKKWIEGLSQQHKRLRSLADHVPHGYRKRSLFEVLIRNNVPLLRATWFIKVTYLNQVRHGSANSLSGAQDKIQLSRTEIWTKDVIDYLQHLLDEFFSRNNSHSTQYSRDRSPQTLYTGSPQQRSDPAAVINSEEPSLHFKWWYMVRLVQWHLAEGLLLPSYIIEWVLNQLKDKELLEILQLVLPIIYGVLETVVSSQTYVRSLVGIATHFIREPSPGGSDLVDNSRRAYTISALAEMLRYLILAVPDTFVALDCFPLPSCVVSYAANDGNFVSKASEDVGKMKNYSTDAICVFRGKAVDAQYQSLSFDNVISAIQRRADNLAKDASPGYPGHSVAKAVQALDKALLQGDIREAYKHLFEDLCDAALDESWIAEVSPCLRSSLKWIGTVSLSSVCSVFFICEWATCDFRDFRTVPPHGMKFTGRKDFSQIYVAIRLLKQKIRDLHTPPRRKSESTLGIIDNLAKGSRQRNNYANRNFQGNGYEIKNNANRLDGLRINSSDIFETPGPLHDIIVCWIDQHEIHKREGVKRVQHFIMELVRAGIFYPQAYVRQLMVSGILDMNGLDLNRRRRHHRILKVLPGLFLRVALEEARIAEGSQLSEAIHVYSNERRLVLHELLFDQSIYVNVAAQNQKRHMAGGRDGASPSLADQWKTIQPTTGISSGRSGKSDADIEELKASIAVILQLPSSSATSADSGLDESQGSVKRSLGAVSSKMDLSEGTPGCEDCKRVKRQKLCEDRSSVLQISSPIHSDDEDLWWVRKGPKPLESYKADPPLKSTKQVSRGRQKTVRRTQSLAQLAAARIEGSQGASTSHVCDNKGSCPHHKTGVEGETLKSMDGVRTACYGDIVSIGKALKKLRYVEKRTVTVWLISIARQHIEEAEKTAAKVGQFNRSFVPVDGRISGRWRLSEDELSAILYFMDVCDDLVSAAKFLLWLLPKVLNSPSSTINSGRNILMLSRNAENHACGVGEAFLLSSLRRYENIIIATDLIPEALSATMHRAAQVMASNGRVSGSAAYGYARYLLKKYGNMASVIEWEKNFKATCDKRLLSELESGRSLDGELGLPLGVPAGIEDPDDYLRQKISGGQLSRVGLSMRDVVHRHMEEAFHYFYDKERKLFAAGSPRNPAIDKSDDESQIAQQIIIGLMDCFRQTGGAAQEGDPSLLSSAVSAIVGNVIPTMVKIHDFTAGSNYQNYASTTGSLSFARRILRIYITCLCLLKEALGERQSRVFEIALATEASCALARVFTPGKAARSQFQSSPEAHDPNANMSNDILNSSSKVASGRTSKVTAAISALVVGAVLHGVTSLERMVTVFRLKEGLDVIQFVRSTKSNSNGSARSIGTFKLDNSIEVHVHWFRLLVGNCRTVSDGLVVEFLGEPSIVALSRMQRMLPLSLVFPPAYLIFAFVLWRPFILNNSLAVREDIHQMYQSLTMAINDAIRHLPFRDVCLRDCQGFYNLVTADSTDAEFAAMLELNGLDLQLKSMAFVPLRARLFLNAIIDCKMPSSLFKPEDFNRVSGHTESKSHRAENEAKLLDKLVHVLDSLQPAKFHWQWVELRLLLNEQALIDRLENHEMSLAEAIRSLSPSPEKAAASENENNFIEIILTRLLVRPDAAPLFSELVHLFGRSLEDSMLLQAKWFLGGHDVLFGRKTIRQRLVNIAESKGLSTKAQFWKPWGWVNSGFGPGLNRGDKKKLEATSLEEGEVVEEGIDSKRHGKGSNPLFDAEGTSIGQQHVTERAFIELVLPCIDQSSDDSRNTFANDLIKQLNNIEQQISAVTRGANKLTGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAPPSPAALRASMSLRLQFLLRLLPLIYTDGEPSGRNMRYLLASVILRLLGSRVVHEDADLSFYPMQSPQSKREVESLPEASSVPSADFSGESLFDRLLLVLYGLLSSCQPSWLRPKPAFKSSNNTSKDSSGFDREIAESLQNDLDHMQLPDTVRWRIQAAIPILLPSVRCSLTCQPPSVPVAALASLQPSISVSGASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGSGDQANLQAASWLKGAIRVRRTDLTYIGAVDDDS
Length2239
PositionKinase
OrganismCitrus sinensis (Sweet orange) (Citrus aurantium var. sinensis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Sapindales> Rutaceae> Aurantioideae> Citrus.
Aromaticity0.07
Grand average of hydropathy-0.275
Instability index51.21
Isoelectric point8.74
Molecular weight248449.37
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00725
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.78|      31|     608|     242|     277|       1
---------------------------------------------------------------------------
  242-  277 (50.27/43.27)	SPQTLYTGSP.........QQR..SDPAAV......INSEEPSLhfkWWymVR
  842-  889 (40.51/21.16)	SKMDLSEGTPgcedckrvkRQKlcEDRSSVlqisspIHSDDEDL...WW..VR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.43|      31|     606|    1301|    1335|       2
---------------------------------------------------------------------------
 1301- 1335 (42.41/45.04)	GNViPTMVKIHDfTAGSNYQNYASttGSLSFARRI
 1912- 1942 (55.02/37.92)	GSV.PSGIEVPS.NKGSNRKSIRG..GSPGLARRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.45|      44|     608|       5|      53|       3
---------------------------------------------------------------------------
    5-   53 (72.20/62.62)	QRSTQLTPYKLKCDKESLNS.RLGPPDFHpQTPN.......C...PEETLTREyvqnGYK
  604-  658 (64.25/40.84)	NRNFQGNGYEIKNNANRLDGlRINSSDIF.ETPGplhdiivCwidQHEIHKRE....GVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.07|      16|     608|     789|     804|       4
---------------------------------------------------------------------------
  789-  804 (26.77/15.67)	ISSGRSGKSDADIEEL
 1408- 1423 (26.30/15.24)	VASGRTSKVTAAISAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.69|      21|     207|     717|     738|       9
---------------------------------------------------------------------------
  717-  738 (32.58/25.27)	LEEARIaEGSQLSEAIHVYSNE
  927-  947 (38.12/24.96)	LAAARI.EGSQGASTSHVCDNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.36|      18|     949|     418|     435|      14
---------------------------------------------------------------------------
  418-  435 (34.93/27.81)	TDAIC....VFR.GKAVDAQYQS
 1364- 1386 (24.43/16.72)	TEASCalarVFTpGKAARSQFQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00725 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGS
2) RHMAGGRDGASPSLADQWKTIQPTTGISSGRSGK
3) TGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAP
2143
763
1911
2206
796
1950










Molecular Recognition Features






MoRF SequenceStartStop




1) IGAVDD
2232
2237