<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00724

Description Uncharacterized protein
SequenceMQRYHPTSCTSAVNNSAISGTSARDATRADSSSLPANFSINSRRSTQLTPYKLKCDKESLNSRLGPPDFHPQTPNCPEETLTREYVQNGYKETVEGLEEVREISLTQAQTFNKPVVLKCREAIRKCLRAINESRAQKRKAGQVYGVPLSDSLLTKPGVFPEQRPCGEEFRKKWIEGLSQQHKRLRSLADHVPHGYRKRSLFEVLIRNNVPLLRATWFIKVTYLNQVRHGSANSLSGAQDKIQLSRTEIWTKDVIDYLQHLLDEFFSRNNSHSTQYSRDRSPQTLYTGSPQQRSDPAAVINSEEPSLHFKWWYMVRLVQWHLAEGLLLPSYIIEWVLNQLKDKELLEILQLVLPIIYGVLETVVSSQTYVRSLVGIATHFIREPSPGGSDLVDNSRRAYTISALAEMLRYLILAVPDTFVALDCFPLPSCVVSYAANDGNFVSKASEDVGKMKNYSTDAICVFRGKAVDAQYQSLSFDNVISAIQRRADNLAKDASPGYPGHSVAKAVQALDKALLQGDIREAYKHLFEDLCDAALDESWIAEVSPCLRSSLKWIGTVSLSSVCSVFFICEWATCDFRDFRTVPPHGMKFTGRKDFSQIYVAIRLLKQKIRDLHTPPRRKSESTLGIIDNLAKGSRQRNNYANRNFQGNGYEIKNNANRLDGLRINSSDIFETPGPLHDIIVCWIDQHEIHKREGVKRVQHFIMELVRAGIFYPQAYVRQLMVSGILDMNGLDLNRRRRHHRILKVLPGLFLRVALEEARIAEGSQLSEAIHVYSNERRLVLHELLFDQSIYVNVAAQNQKRHMAGGRDGASPSLADQWKTIQPTTGISSGRSGKSDADIEELKASIAVILQLPSSSATSADSGLDESQGSVKRSLGAVSSKMDLSEGTPGCEDCKRVKRQKLCEDRSSVLQISSPIHSDDEDLWWVRKGPKPLESYKADPPLKSTKQVSRGRQKTVRRTQSLAQLAAARIEGSQGASTSHVCDNKGSCPHHKTGVEGETLKSMDGVRTACYGDIVSIGKALKKLRYVEKRTVTVWLISIARQHIEEAEKTAAKVGQFNRSFVPVDGRISGRWRLSEDELSAILYFMDVCDDLVSAAKFLLWLLPKVLNSPSSTINSGRNILMLSRNAENHACGVGEAFLLSSLRRYENIIIATDLIPEALSATMHRAAQVMASNGRVSGSAAYGYARYLLKKYGNMASVIEWEKNFKATCDKRLLSELESGRSLDGELGLPLGVPAGIEDPDDYLRQKISGGQLSRVGLSMRDVVHRHMEEAFHYFYDKERKLFAAGSPRNPAIDKSDDESQIAQQIIIGLMDCFRQTGGAAQEGDPSLLSSAVSAIVGNVIPTMVKIHDFTAGSNYQNYASTTGSLSFARRILRIYITCLCLLKEALGERQSRVFEIALATEASCALARVFTPGKAARSQFQSSPEAHDPNANMSNDILNSSSKVASGRTSKVTAAISALVVGAVLHGVTSLERMVTVFRLKEGLDVIQFVRSTKSNSNGSARSIGTFKLDNSIEVHVHWFRLLVGNCRTVSDGLVVEFLGEPSIVALSRMQRMLPLSLVFPPAYLIFAFVLWRPFILNNSLAVREDIHQMYQSLTMAINDAIRHLPFRDVCLRDCQGFYNLVTADSTDAEFAAMLELNGLDLQLKSMAFVPLRARLFLNAIIDCKMPSSLFKPEDFNRVSGHTESKSHRAENEAKLLDKLVHVLDSLQPAKFHWQWVELRLLLNEQALIDRLENHEMSLAEAIRSLSPSPEKAAASENENNFIEIILTRLLVRPDAAPLFSELVHLFGRSLEDSMLLQAKWFLGGHDVLFGRKTIRQRLVNIAESKGLSTKAQFWKPWGWVNSGFGPGLNRGDKKKLEATSLEEGEVVEEGIDSKRHGKGSNPLFDAEGTSIGQQHVTERAFIELVLPCIDQSSDDSRNTFANDLIKQLNNIEQQISAVTRGANKLTGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAPPSPAALRASMSLRLQFLLRLLPLIYTDGEPSGRNMRYLLASVILRLLGSRVVHEDADLSFYPMQSPQSKREVESLPEASSVPSADFSGESLFDRLLLVLYGLLSSCQPSWLRPKPAFKSSNNTSKDSSGFDREIAESLQNDLDHMQLPDTVRWRIQAAIPILLPSVRCSLTCQPPSVPVAALASLQPSISVSGASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGSGDQANLQAASWLKGAIRVRRTDLTYIGAVDDDS
Length2277
PositionKinase
OrganismCitrus sinensis (Sweet orange) (Citrus aurantium var. sinensis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Sapindales> Rutaceae> Aurantioideae> Citrus.
Aromaticity0.07
Grand average of hydropathy-0.281
Instability index51.31
Isoelectric point8.76
Molecular weight252360.43
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00724
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.78|      31|     608|     280|     315|       1
---------------------------------------------------------------------------
  280-  315 (50.27/48.63)	SPQTLYTGSP.........QQR..SDPAAV......INSEEPSLhfkWWymVR
  880-  927 (40.51/23.84)	SKMDLSEGTPgcedckrvkRQKlcEDRSSVlqisspIHSDDEDL...WW..VR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     168.52|      55|     606|      29|      91|       2
---------------------------------------------------------------------------
   29-   91 (85.21/70.62)	ADSSSLPANFsinSRRSTQLTPYKLKCDKESLNS.RLGPPDFHpQTPN.......C...PEETLTREyvqnGYK
  631-  696 (83.31/48.49)	AKGSRQRNNY...ANRNFQGNGYEIKNNANRLDGlRINSSDIF.ETPGplhdiivCwidQHEIHKRE....GVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.43|      31|     608|    1339|    1373|       3
---------------------------------------------------------------------------
 1339- 1373 (42.41/34.95)	GNViPTMVKIHDfTAGSNYQNYASttGSLSFARRI
 1950- 1980 (55.02/29.41)	GSV.PSGIEVPS.NKGSNRKSIRG..GSPGLARRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.07|      16|     608|     827|     842|       4
---------------------------------------------------------------------------
  827-  842 (26.77/13.64)	ISSGRSGKSDADIEEL
 1446- 1461 (26.30/13.26)	VASGRTSKVTAAISAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.69|      21|     207|     755|     776|       9
---------------------------------------------------------------------------
  755-  776 (32.58/29.77)	LEEARIaEGSQLSEAIHVYSNE
  965-  985 (38.12/29.40)	LAAARI.EGSQGASTSHVCDNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.36|      18|     949|     456|     473|      14
---------------------------------------------------------------------------
  456-  473 (34.93/23.84)	TDAIC....VFR.GKAVDAQYQS
 1402- 1424 (24.43/14.31)	TEASCalarVFTpGKAARSQFQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00724 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGS
2) MQRYHPTSCTSAVNNSAISGTSARDATRADSSSLPANFSIN
3) RHMAGGRDGASPSLADQWKTIQPTTGISSGRSGK
4) TGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAP
2181
1
801
1949
2244
41
834
1988










Molecular Recognition Features






MoRF SequenceStartStop




1) IGAVDD
2270
2275