<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00602
Description |
Mediator of RNA polymerase II transcription subunit 19 |
Sequence | MSFHPRTPQSPSQFSPGTSDLTSSMNSTVPSTTTTLPTPAHSVNGSASQPSDMSQDIVMGDDSPHKRKRSLEDLGDREQKKAHIEDSKTGIEALHLDVGEKYLLCQTPHHERLPRITEDLFEMFNLTGIAAEVAREKPNGEKNALRKTYKGQIKKLGILGRFDSVAQDWDAPRESDGDKKREVYHGFRELLEIPDAEFWGTRQDPITNGLSSTVKFNLSKATAMAKGPIPVKDWDSAVLGDIPPGGMDALKQGLAGKATAPGTPSATTPNPFMRKQQQGPPGAVRPQRTKKRGYGENTYEGYGEGFPDDGYSTGDGDDRGGQKRRKKVGSAAALPSLSLSDPLQDGGSGQVFPNTMRPQGYGAVGA |
Length | 366 |
Position | Head |
Organism | Colletotrichum sublineola (Sorghum anthracnose fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum>
Colletotrichum graminicola species complex.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.833 |
Instability index | 43.38 |
Isoelectric point | 7.11 |
Molecular weight | 39517.54 |
Publications | PubMed=24926053
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364151
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP00602
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 72.98| 19| 64| 277| 295| 1
---------------------------------------------------------------------------
277- 295 (36.61/19.75) QQGPPGAVRPQRTKKRGYG
344- 362 (36.37/19.58) QDGGSGQVFPNTMRPQGYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 37.22| 11| 34| 139| 151| 2
---------------------------------------------------------------------------
139- 151 (15.92/16.96) NGEKNalRKTYKG
176- 186 (21.30/14.49) DGDKK..REVYHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 82.86| 26| 35| 193| 223| 3
---------------------------------------------------------------------------
193- 219 (42.01/21.82) IPDAEfWGTR.QDPITNGLSSTVKFNLS
229- 255 (40.85/21.26) IPVKD.WDSAvLGDIPPGGMDALKQGLA
---------------------------------------------------------------------------
|