<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00595

Description Uncharacterized protein
SequenceMTANFWSSTHAQRWIFTRSQLLLAREEDLRYATPEEVGAIGIWGANVISTLSKRMQLRQRVSATATVFFKRFYAKNSYCATDLTIVIAACVYVAAKVEESPVHVRSVFAEASRVFADMSSRSFPTAAHAVAEMEFYLLEELEFDLILHHPYRTLAQIASTIGNINVKDSKISAVNSTEKESLGPSSRKRKHSRSEQDRALRRARHASQTDRELIIGGSVNNGSIAASDAQDIDEEPCLEDFDDSALQMAWFVLNDTYRSDIPLLYPPHLIAIASVLLALVLHPPASEKLEASISQMQSARNAWEQSKLHNQAIRPGQDGTTSDASGNPGALSPQASRIVGLGIDNKATPITSDRLDHTASNGAVIRSFAAQVPSTTSPVASTPGSVGSMFTSSGNTPANTPGVATHPQLGAGQPTATVAIPHQPPVPPPDTLTVLASLNVSMPLVAEIVQEILSSYELWNRVGSSSGSSSATGGATAGASRDKATGKRATLHSASDKQGEDIVGNGRAMMKRLERMREARRRDILARGKS
Length530
PositionKinase
OrganismTilletiaria anomala (strain ATCC 24038 / CBS 436.72 / UBC 951)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Georgefischeriales> Tilletiariaceae> Tilletiaria.
Aromaticity0.05
Grand average of hydropathy-0.268
Instability index51.78
Isoelectric point7.81
Molecular weight57051.50
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00595
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     241.57|      49|     142|     314|     362|       1
---------------------------------------------------------------------------
  266-  296 (35.92/15.92)	..............................PPHLIAIASVLLALVLH.....PPASEKL.EA...SISQM
  314-  362 (83.61/46.74)	R................PGQDGTTSDASGNPGALSPQASRIVGLGIDNKAT.PITSDRL.DH...TASNG
  366-  430 (60.90/32.06)	RsfaaqvpsttspvastPGSVGSMFTSSGNTPANTPGVATHPQLGAGQ....PTATVAI.PHqppVPPPD
  461-  506 (61.15/32.23)	R................VGSSSGSSSATG..GA.TAGASRDKATG..KRATlHSASDKQgED...IVGNG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00595 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AQVPSTTSPVASTPGSVGSMFTSSGNTPANTPGVATHPQLGAGQPTATVAIPHQPPVPPPDTLTVLA
2) GSSSGSSSATGGATAGASRDKATGKRATLHSASDKQGEDIVGNGRAMMKRLERMREARRRDILARGKS
3) WEQSKLHNQAIRPGQDGTTSDASGNPGALSPQASRI
370
463
303
436
530
338

Molecular Recognition Features

MoRF SequenceStartStop
1) IVGNGRAM
2) KRATLH
502
487
509
492