<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00592

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMSPNYWDSTQRRHWLFTKDQLASMRQKLDDDHADLVRMFPLPQPRHLAIYFNQQLLRLAKRLSIRQQAMATAQVYLKRFYIKVPIRSTNPYLVITTAIYLACKMEEAPQHIRLIVTEARQLWQDFIGLDTSKIGECEFYLISEMSSQLIVHQPYRTLTLLRAELSLVDDDVQLARSVINDSFNSDLPLICAPHIIALVAILLALVLRPNSSRAGQATSGSAAAAGLAAAQAALSQAHGRNGGGGGGGGSGTPLDSAAAGPESKEKQQEARISRVQHFAAWLAESSVDIPAMVDATQEMISLYDLYEQYNEKLTREQINRFVKARGLDK
Length328
PositionKinase
OrganismUstilaginoidea virens (Rice false smut fungus) (Villosiclava virens)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Clavicipitaceae> Ustilaginoidea.
Aromaticity0.07
Grand average of hydropathy-0.183
Instability index51.10
Isoelectric point8.36
Molecular weight36549.41
Publications
PubMed=24846013
PubMed=27151791

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00592
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.57|      26|      26|     206|     231|       2
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  206-  231 (41.47/23.27)	LRPNSSRAGQATSGSAAAAGLAAAQA
  233-  258 (46.10/26.56)	LSQAHGRNGGGGGGGGSGTPLDSAAA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00592 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HGRNGGGGGGGGSGTPLDSAAAGPESKEKQQEA
237
269










Molecular Recognition Features






MoRF SequenceStartStop




1) AAGLAAAQAALS
223
234