<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00583

Description Heat shock protein 70B
SequenceMATKTEGKAIGIDLGTTYSCVGVWMNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPENTVFDAKRLIGRRFSDPSVQSDVKLWPFRVIPGPGDKPMIVVRYKGEEKQFSAEEVSSMVLTKMKEVAEAFLGHTVKNAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKASRKGEQNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVAEFRRKHKKDISGNARALRRLRTACERAKRTLSSTTQTTIEIDSLFEGIDFYATITRARFEELNMDLFRKCMEPVEKCLKDAKIDKGQVHEVVLVGGSTRIPKIQKMLQDFFNGKELCKSINPDEAVACGAAVQAAILTGEGDEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQINVTFDIDANGILNVTAEDKTAGVKNQITITNDKGRLSKEEIEKMVKDAERYKAEDEEVKKKVEAKNALENYAYNMRNTVRDEKFAAKLSPEDREKIEKAVEETIEWLDRNQLAEVDELEDRLKELESICNPIISKMYQGGAADGDVPMGGGGYTGSGSGSGPGPKIEEVD
Length650
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.06
Grand average of hydropathy-0.419
Instability index34.77
Isoelectric point5.25
Molecular weight71498.30
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00583
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     266.84|      87|     195|     248|     340|       3
---------------------------------------------------------------------------
  248-  340 (130.11/109.40)	VAEFRRKHKKDisGNARALRRLrTACERAKRTLSStTQTTIEIDSlfEGI.DFYATITRARFEE...LNMDLFRKCMEPVEKCLKDAKIDKGQVHEV
  448-  538 (136.73/92.86)	VYEGERARTKD..NNLLGKFEL.TGIPPAPRGVPQ.INVTFDIDA..NGIlNVTAEDKTAGVKNqitITNDKGRLSKEEIEKMVKDAERYKAEDEEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.66|      17|      21|      38|      55|       4
---------------------------------------------------------------------------
   38-   55 (25.98/18.49)	NRT..TPSYVAFtDTERLIG
   60-   78 (24.68/12.95)	NQVamNPENTVF.DAKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.76|      13|     392|     227|     239|       5
---------------------------------------------------------------------------
  227-  239 (24.85/12.26)	ATAGDTHLGGEDF
  621-  633 (25.91/13.07)	AADGDVPMGGGGY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00583 with Med37 domain of Kingdom Viridiplantae
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