<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00574

Description Mediator subunit 8 isoform 2
SequenceMEGMIQDPSQQQQAQQKNQVVAGAERLNQAVQQQLNLESLKTRAISLFKAISRILEDFDAYSRTNTTPKWLDILGQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENASILPVMLSSKLLPEMETEDNLKREQLLQGMQNLPIPSQIEKLKTRIDMIGAACESAEKVLADTRKAYCFGSRQGPAILPTLDKGQAAKIQEQENLLRAAVNFGEGLHLPADQRQITPSLPLHLADIMPAADGVHSFSDPSGMYMKNTPLTSSNIGSQGSLVQASGAQLIGRSAASPSAATSATSFDNTTNSPLPYANSPRSGTNMMNTPSPQQQTQQQQQQQQQQQQQQQQQQQRQKMMQLPQHQLLAQQQFRQSTMQGLGQNQLPLHDLQGQTQQKFQSMQFSQPLAHQQYQGRQLPPGHVQHGIGQSQLNQGNQLGRHLSQFSSPANSALYNAAQGTPSTQMIPNMSATMPSQSLLPRMQFGLPGGNPQRSHASQILTDQMFNMGSGPGGMMPMQPQQQQQQQQHGSQGAFSNMPTAQNLQSNMVALQNNPQSHPNFAQQRQQGQQ
Length558
PositionHead
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.04
Grand average of hydropathy-0.719
Instability index62.24
Isoelectric point9.10
Molecular weight61502.42
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00574
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     305.43|     104|     186|     180|     364|       1
---------------------------------------------------------------------------
  180-  313 (150.93/58.73)	GSRQGPaiLPTLD.KGQA.AKIQeqenllraAVNFGEGL.HLPADQRQITPSLPLH...LADIMPAAD.GVH..SFSDP..SGMYmkNTPltssnigsQGSlvqaSGAQLIGR.SAASPSAA.TSATSFDnttnspLPYANSPRSGT
  369-  485 (154.50/69.07)	GLGQNQ..LPLHDlQGQTqQKFQ........SMQFSQPLaHQQYQGRQLPPGHVQHgigQSQLNQGNQlGRHlsQFSSPanSALY..NAA........QGT....PSTQMIPNmSATMPSQSlLPRMQFG......LPGGNPQRSHA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.31|      15|      15|     322|     336|       2
---------------------------------------------------------------------------
  322-  336 (29.43/ 8.13)	QQQTQQQQQQQQQQQ
  338-  352 (28.88/ 7.83)	QQQQQQQRQKMMQLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.58|      21|     497|       3|      41|       3
---------------------------------------------------------------------------
    3-   24 (34.81/ 6.36)	GMIQDPSQQQQAQQKNQVvAGA
  502-  522 (41.93/ 6.90)	GMMPMQPQQQQQQQQHGS.QGA
  547-  558 (10.83/10.06)	.....PNFAQQRQQGQQ.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.67|      31|     113|      28|      61|       4
---------------------------------------------------------------------------
   28-   61 (43.34/40.24)	NQAVQQQLnlESLKTRaISLFKAI....SRILEDF.DAY
  142-  177 (43.33/28.46)	NLPIPSQI..EKLKTR.IDMIGAAcesaEKVLADTrKAY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00574 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IMPAADGVHSFSDPSGMYMKNTPLTSSNIGSQG
2) LVQASGAQLIGRSAASPSAATSATSFDNTTNSPLPYANSPRSGTNMMNTPSPQQQTQQQQQQQQQQQQQQQQQQQRQKMMQLPQHQLLAQQQFRQSTMQGLGQNQLPLHDLQGQTQQKFQSMQFSQPLAHQQYQGRQLPPGHVQHGIGQSQLNQGNQLGRHLSQFSSPANSALYNAAQGTPSTQMIPNMSATMPSQSLLPRMQFGLPGGNPQRSHASQILTDQMFNMGSGPGGMMPMQPQQQQQQQQHGSQGAFSNMPTAQNLQSNMVALQNNPQSHPNFAQQRQQGQQ
236
270
268
558










Molecular Recognition Features






MoRF SequenceStartStop




NANANA