<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00568

Description RNA polymerase transcriptional regulation mediator-related isoform 1
SequenceMATPPVAPPQAAAAGNFEAPPPLPMQPPGTDMTGICFRDQLWLNTYPLDRNLIFDYFALSPFYDWTCNNEQLRMHSIHPLDISQLSKMTGVEYMLSEVMEPNLFVIRKQKRDGPEKVTPMLAYYILDGSIYQAPQLCNVFAARVGRALYYISKAFTTAASKLEKIGYVDTENESETFESKGGKETIDFKEVKRVDHILASLQRKLPPAPPPPPFPEGFIPLATAEAEKDPENQQAVETQPPAIDPIIDQGPAKRMKF
Length257
PositionHead
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.10
Grand average of hydropathy-0.374
Instability index53.42
Isoelectric point5.11
Molecular weight28774.68
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00568
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.93|      10|     188|      19|      29|       1
---------------------------------------------------------------------------
   19-   29 (19.02/10.24)	APPPLPMqPPG
  208-  217 (22.91/ 8.46)	APPPPPF.PEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.41|      14|      31|      36|      49|       2
---------------------------------------------------------------------------
   36-   49 (29.12/21.65)	CFRDQLWLNT.YPLD
   67-   81 (22.29/14.82)	CNNEQLRMHSiHPLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00568 with Med6 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SLQRKLPPAPPPPPFPEGFIPLATAEAEKDPENQQAVETQPPAIDPIIDQGP
200
251










Molecular Recognition Features






MoRF SequenceStartStop




1) AKRMKF
2) GFIPLATA
3) KRVDHILASLQRKL
252
217
192
257
224
205