<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00564

Description Mediator subunit 8 isoform 1
SequenceMEGMIQDPSQQQQAQQKNQVVAGAERLNQAVQQQLNLESLKTRAISLFKAISRILEDFDAYSRTNTTPKWLDILGQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENASILPVMLSSKLLPEMETEDNLKREQLLQGMQNLPIPSQIEKLKTRIDMIGAACESAEKVLADTRKAYCFGSRQGPAILPTLDKGQAAKIQEQENLLRAAVNFGEGLHLPADQRQITPSLPLHLADIMPAADGVHSFSDPSGMYMKNTPLTSSNIGSQGSLVQASGAQLIGRSAASPSAATSATSFDNTTNSPLPYANSPRSGTNMMNTPSPQQQTQQQQQQQQQQQQQQQQQQQRQKMMQLPQHQLLAQQQFRQSTMQGLGQNQLPLHDLQGQTQQKFQSLHGQMQFSQPLAHQQYQGRQLPPGHVQHGIGQSQLNQGNQLGRHLSQFSSPANSALYNAAQGTPSTQMIPNMSATMPSQSLLPRMQFGLPGGNPQRSHASQILTDQMFNMGSGPGGMMPMQPQQQQQQQQHGSQGAFSNMPTAQNLQSNMVALQNNPQSHPNFAQQRQQGQQ
Length562
PositionHead
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.04
Grand average of hydropathy-0.720
Instability index61.69
Isoelectric point9.10
Molecular weight61937.90
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00564
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     246.71|      40|      40|     437|     476|       3
---------------------------------------------------------------------------
  246-  289 (28.15/ 7.35)	.FSDPSGmymknTPLTSsniGSQGSLvqasGAQLIGR.SA....ASP.........................................SA......A
  294-  371 (37.10/12.11)	SFDNTTN.....SPLPY...ANSPRS....GTNM...MNT....PSPqqqtqqqqqqqqqqqqqqqqqqqrqkmmqlpqhqllaqqqfRQSTMQGLG
  372-  395 (34.42/10.68)	QNQLP.........L.H...DLQG.Q.............T....QQK.........................................FQSLHGQM.
  437-  476 (70.52/29.91)	QFSSPAN.....SALYN...AAQGTP....STQMIPNMSA....TMP.........................................SQSLLPRMQ
  479-  515 (44.17/15.87)	...LPGG.....NPQRS...HASQIL....TDQMF.NMGSgpggMMP.........................................MQ...PQQQ
  520-  544 (32.36/ 9.58)	...............QH...GSQGAF....S.....NMPT....AQN.........................................LQSNMVALQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.19|      41|     113|      16|      61|       4
---------------------------------------------------------------------------
   16-   61 (53.35/44.83)	QKNQVVAGAERLnqAVQQQlnLESLKTRaISLFKAI....SRILEDF.DAY
  132-  177 (59.84/33.71)	KREQLLQGMQNL..PIPSQ..IEKLKTR.IDMIGAAcesaEKVLADTrKAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.77|      10|     150|     398|     410|       8
---------------------------------------------------------------------------
  398-  410 (14.93/12.43)	SQPlahQQYQGRQ
  421-  430 (18.84/ 7.06)	GQS...QLNQGNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.81|      10|      28|     204|     217|       9
---------------------------------------------------------------------------
  204-  217 (11.67/19.81)	NLLRAAvnfgEGLH
  235-  244 (19.14/13.14)	DIMPAA....DGVH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00564 with Med8 domain of Kingdom Viridiplantae
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