<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00555

Description Heat shock protein 70 (Hsp 70) family protein
SequenceMAGSWRASGSLVVLAIVLSGCLFAISIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDNERLIGEAAKNQAAVNAERTIFDVKRLIGRKFEDKEVQKDMKLVPYKIVNKDGKPYIQVKIKDGETKVFSPEEISAMVLTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGIIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDHRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRALSSQHQVRVEIESLFDGIDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKRQIDEIVLVGGSTRIPKVQQLLKDYFEGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIDRMVREAEEFAEEDKKVKEKIDARNSLETYVYNMKNQINDKDKLADKLESDEKEKVETAVKEALEWLDDNQSAEKEDYEEKLKEVEAVCNPIITAVYQRSGGAPGGESTEEDDSHDEL
Length665
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.06
Grand average of hydropathy-0.444
Instability index27.02
Isoelectric point5.14
Molecular weight73314.27
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00555
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.13|      27|      27|     561|     587|       1
---------------------------------------------------------------------------
  561-  587 (44.87/26.13)	DKKVKEKIDARNSLETYVYNMKNQIND
  598-  616 (31.60/16.53)	DEKEK........VETAVKEALEWLDD
  626-  645 (26.66/12.97)	EEKLKEVEAVCNPIITAVYQ.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.02|      11|      27|     232|     242|       2
---------------------------------------------------------------------------
  232-  242 (20.52/11.98)	LGGGTFDVSIL
  260-  270 (22.49/13.82)	LGGEDFDHRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.40|      14|      27|     101|     114|       3
---------------------------------------------------------------------------
   78-   91 (21.30/12.16)	DNERLIGEAAKNQA
  101-  114 (23.50/14.18)	DVKRLIGRKFEDKE
  130-  143 (23.61/14.28)	DGKPYIQVKIKDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.40|      20|      22|     492|     513|       4
---------------------------------------------------------------------------
  494-  513 (37.00/24.72)	TGI...PPAPRGTPQIE.VTFEVD
  515-  538 (24.40/ 8.29)	NGIlnvKAEDKGTGKSEkITITND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.62|      26|      27|     387|     412|       5
---------------------------------------------------------------------------
  196-  223 (32.70/19.86)	II..AGLNVARII.NePTaAA.IAYGLDKKGG
  387-  410 (37.01/23.49)	....EGKEPNKGV.N.PD.EA.VAYGAAVQGG
  411-  440 (25.91/14.15)	ILsgEGGDETKDIlL.LD.VApLTLGIETVGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.03|      13|     188|     283|     295|       6
---------------------------------------------------------------------------
  283-  295 (22.19/12.53)	KDISKDNRALGKL
  479-  491 (23.83/13.94)	RSLTKDCRLLGKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.82|      13|     188|     161|     179|       7
---------------------------------------------------------------------------
  147-  159 (21.50/22.59)	FSPEEISAMVLTK
  167-  179 (20.32/ 7.61)	FLGKKIKDAVVTV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00555 with Med37 domain of Kingdom Viridiplantae
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