<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00538

Description U-box domain-containing protein kinase family protein isoform 1
SequenceMEKKEIVEAEGEPVPVLPPPPTLNIGIAINGNRKSKYVVKWALEKFITEENVMFKLLHVRAKITTVPTPMGNFIPISQVRNDVAAAYKKEVEWQTNEMLLPYKKMCAQRKGQVDVIVIESNDVANAIAEEVTKSTITKLVIGATSRGMFTRKLKKNNLSSRISVCTPSFCTVYAVSKGQLSSIRPSDSETNVSTKDDSSETSVSCKSSSSYTFSSETELGSVASYATFHSPSLPVQRFQALSTINQTFLHSSTSSLEINQSRSLESTQSRSPDINHSRCHSLDIVAGKDDMSTCRSSSETRQAVSRSSSCRSLPTDQQSVLSDQISTSDVLTDNSFSEHQVYVNFELEKLRTELRHVQGMYAIAQSETIDASRKLNALRKHRLEEAMKFKEISFKEEKAEELARQEKEKYEAARREVEHVKECADREASQRREAEMKAFHDAKEKEKLENVLIGSVQQYQKFTWEEIVSATSSFSEDLKVGMGAYGTVYKCMLHHTAVAVKVLRSKENSRTKQFQQELEILSKIRHPHLLLLLGACPEFPDHGCLVYEYMENGSLEERLLRKNNTPPIPWFERYRIAWEVASALNFLHNSKPEPIIHRDLKPANILLDRNFVSKIGDVGLSMMLNADPLSSSTMYRDTGPVGTLCYIDPEYQRTGLISPKSDVYAFGMVILQLLTAKPAIALTHVVETAIDDGNLPGILDSEAGPWPVEETRELAILGLSCAELRRKDRPGLKDQVLPVLERMKEVADRARISISKVQSAPPNHFICPILKDVMDDPCVAADGYTYDRKAIEKWLDGNDKSPMTNLPLLNKNLLPNYNLLSAIVEWKSRKQ
Length831
PositionTail
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.06
Grand average of hydropathy-0.425
Instability index47.17
Isoelectric point6.85
Molecular weight93361.36
Publications
PubMed=23731509

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00538
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.23|      27|      72|     181|     207|       1
---------------------------------------------------------------------------
  181-  207 (46.39/30.44)	SSIRPSDSETNVSTKDDSSETSVS.CKS
  254-  280 (35.19/21.18)	SSLEINQSRSLESTQSRSPDINHSrCH.
  281-  296 (23.65/11.64)	.SLDI......VAGKDDMS....T.CRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.63|      24|      26|     375|     400|       2
---------------------------------------------------------------------------
  375-  400 (33.23/31.20)	LNALRKHRLEEAMkfKEISFKEEKAE
  402-  425 (39.39/28.81)	LARQEKEKYEAAR..REVEHVKECAD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.03|      40|     332|     310|     367|       5
---------------------------------------------------------------------------
  310-  357 (56.46/46.30)	CRSLPTDQQSVLsdqIS.TSDVltdnsFSEHQVYVNFELEKLRTELRHV
  645-  685 (64.57/33.66)	CYIDPEYQRTGL...ISpKSDV.....YAFGMVILQLLTAKPAIALTHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.36|      20|     333|     107|     147|       6
---------------------------------------------------------------------------
   81-  100 (35.41/34.24)	NDVAAAYKKEVEWQTNEMLL
  121-  140 (31.95/20.52)	NDVANAIAEEVTKSTITKLV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00538 with Med32 domain of Kingdom Viridiplantae
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