<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00530

Description Pre-mRNA-processing protein 40A isoform 4
SequenceMANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPWLSSGNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKKTRQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYYNKVTKQSKWTIPEELKLAREQAQVVASQGAPSDTGVASQAPVAGAVSSAEMPAAAIPVSSNTSQASSPVSVTPVAAVANPSPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYANKQEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVELERKERENAAEEKRRNIAEYRKFLESCDFIKVQHFQKRIQANSQWRKVQDRLEDDERCSRLEKIDRLVMFQDYIHDLEKEEEEKKKMQKEQLRRAERKNRDAFRKLMDEHVVDGTLTAKTYWRDYCLKVKDLPPYLAVASNTSGSTPKDLFEDVVEELEKQYQQDKTHIKDAMKSGKISMVSTWTVEDFKAAISEDVGSLPISDINLKLVYEELLKSAKEKEEKEAKKRQRLADDFTKLLHTYKVCYIVL
Length844
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.07
Grand average of hydropathy-0.734
Instability index55.00
Isoelectric point7.65
Molecular weight93910.14
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00530
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     274.06|      38|      38|     216|     253|       1
---------------------------------------------------------------------------
    7-   41 (40.57/16.80)	.......P......S.SAqPHW.....PPA....................VGSLGPQSYGSPLSSQFRPVVPMQ
   45-   82 (39.54/16.19)	..HF...V......P.AA.SQQfrpvgQVP....................SSNVGMPAVQNQ...QMQFSQPMQ
  100-  156 (28.18/ 9.45)	PMHV...PfgqtnrPlTS.GSP.....QSHqtapplnshmpglgapgmppSSS....YSY....VPSSFGQPQN
  169-  205 (37.16/14.78)	QVHAsvaP......V.AG.QPW............................LSSGNQSVSLAIPIQQTGQQPPL.
  216-  253 (69.93/34.24)	PIHT...P......P.SA.SDW.....QEH....................TSADGRRYYYNKKTRQSSWEKPLE
  257-  294 (58.69/27.56)	PIER...A......D.AS.TVW.....KEF....................TTPEGRKYYYNKVTKQSKWTIPEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.89|      35|      38|     320|     357|       2
---------------------------------------------------------------------------
  321-  358 (49.79/35.17)	PVAGAVSSAEMpaAAIPVSS...NTSQASSPVSvTPVAAVA
  360-  392 (50.14/25.81)	PSPTLVSGSTV....VPVSQ...SAATNASEVQ.SPAVAVT
  393-  418 (26.95/10.17)	PLP.AVSSGG...STTPVTSvnaNTTMIRS...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      86.61|      16|      16|     556|     571|       3
---------------------------------------------------------------------------
  556-  571 (25.36/14.04)	LTSSMRWSKAQSLFEN
  575-  590 (20.87/10.39)	FKAVERARDREDLFEN
  595-  610 (17.84/ 7.93)	LERKERENAAEEKRRN
  633-  648 (22.54/11.75)	IQANSQWRKVQDRLED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.86|      12|      38|      85|      96|       4
---------------------------------------------------------------------------
   85-   96 (26.38/15.44)	PP.RPNQPGLSAP
  124-  136 (22.48/11.93)	PPlNSHMPGLGAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     153.84|      47|      55|     723|     772|       6
---------------------------------------------------------------------------
  694-  714 (21.12/ 6.49)	....................RDA.FRKLMDE..........HVVDGTLTAKT
  723-  772 (72.93/48.23)	VKDlppYLAVASNTSGSTP.KDL.FEDVVEELEKQYQQDKTHIKDAMKSGKI
  780-  826 (59.79/32.09)	VED...FKAAISEDVGSLPiSDInLKLVYEELLKSAKEKEE..KEAKKRQRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00530 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKK
2) MANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPW
3) SAEMPAAAIPVSSNTSQASSPVSVTPVAAVA
4) SPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYAN
186
1
328
361
242
182
358
471










Molecular Recognition Features






MoRF SequenceStartStop




1) GRKYYYN
2) GRRYYYN
275
234
281
240