<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00525

Description Pre-mRNA-processing protein 40A isoform 8
SequenceMANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPWLSSGNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKKTRQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYYNKVTKQSKWTIPEELKLAREQAQVVASQGAPSDTGVASQAPVAGAVSSAEMPAAAIPVSSNTSQASSPVSVTPVAAVANPSPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYANKQEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVELERKERENAAEEKRRNIAEYRKFLESCDFIKANSQWRKVQDRLEDDERCSRLEKIDRLVMFQDYIHDLEKEEEEKKKMQKVEEQLRRAERKNRDAFRKLMDEHVVDGTLTAKTYWRDYCLKVKDLPPYLAVASNTSGSTPKDLFEDVVEELEKQVCASNLFSARFDVYFFLLHYSSLQQRTNDFHTFFMVSFLHE
Length789
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.08
Grand average of hydropathy-0.700
Instability index58.39
Isoelectric point6.45
Molecular weight87659.83
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00525
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     291.16|      38|      38|     216|     253|       1
---------------------------------------------------------------------------
   45-   82 (39.19/20.22)	..HF...VPAASQQfrpvgQVPSSNVGMPAVQNQ...QMQFSQPMQ
  100-  127 (45.67/25.01)	PMHV...PFGQTN......RPLTSGSP.......QSHQTA..PPLN
  136-  156 (36.49/18.23)	P.GM...PPSSS.Y.....S...........Y....VPSSFGQPQN
  169-  205 (38.67/19.84)	QVHAsvaPVAGQPW........LSSGNQSVSLAIPIQQTGQQPPL.
  216-  253 (70.68/43.47)	PIHT...PPSASDW.....QEHTSADGRRYYYNKKTRQSSWEKPLE
  257-  294 (60.46/35.93)	PIER...ADASTVW.....KEFTTPEGRKYYYNKVTKQSKWTIPEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.55|      17|      17|     321|     337|       2
---------------------------------------------------------------------------
  321-  337 (28.12/12.90)	PVAGAVSSAEM..PAAAIP
  354-  372 (19.43/ 6.66)	VAAVANPSPTLvsGSTVVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     347.57|      65|      65|     545|     609|       3
---------------------------------------------------------------------------
  479-  541 (89.09/58.84)	.FKSLL.E...SANVQSDWTWEQTMREIINDKRYGAL...KTLGERKQAFNEYLGQRKKLEAEERRMRQ.........KK
  545-  609 (101.02/67.75)	EFTKMLEE...SKELTSSMRWSKAQSLFENDERFKAV...ERARDREDLFENYIVELERKERENAAEEK.........RR
  613-  685 (94.40/62.81)	EYRKFLES...CDFIKANSQWRKVQDRLEDDERCSRL...EKI.DRLVMFQDYIHDLEKEEEEKKKMQKveeqlrraeRK
  689-  748 (63.05/39.41)	AFRKLMDEhvvDGTLTAKTYWRDYCLKVKDLPPYLAVasnTSGSTPKDLFEDVVEELEKQ....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.17|      16|      38|     338|     353|       5
---------------------------------------------------------------------------
  338-  353 (27.28/15.08)	VSSNTSQASSPVSVTP
  394-  405 (17.78/ 7.21)	LPA....VSSGGSTTP
  406-  421 (18.10/ 7.48)	VTSVNANTTMIRSLES
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00525 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKK
2) MANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPW
3) SAEMPAAAIPVSSNTSQASSPVSVTPVAAVA
4) SPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYAN
186
1
328
361
242
182
358
471










Molecular Recognition Features






MoRF SequenceStartStop




NANANA