<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00523

Description Pre-mRNA-processing protein 40A isoform 6
SequenceMANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPWLSSGNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKKTRQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYYNKVTKQSKWTIPEELKLAREQAQVVASQGAPSDTGVASQAPVAGAVSSAEMPAAAIPVSSNTSQASSPVSVTPVAAVANPSPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYANKQEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVELERKERENAAEEKRRNIAEYRKFLESCDFIKVQHFQKRIQANSQWRKVQDRLEDDERCSRLEKIDRLVMFQDYIHDLEKEEEEKKKMQKEQLRRAERKNRDAFRKLMDEHVVDGTLTAKTYWRDYCLKVKDLPPYLAVASNTSGSTPKDLFEDVVEELEKQYQQDKTHIKDAMKSGKVRY
Length774
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.07
Grand average of hydropathy-0.780
Instability index58.41
Isoelectric point8.35
Molecular weight85926.97
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00523
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     223.02|      38|      38|     216|     253|       1
---------------------------------------------------------------------------
    5-   44 (39.72/18.43)	SQPSS..........aqP.HW...PPAVGSL...gpQSygsPLSSQFRPVV...PMQQGQ.
   45-   77 (30.57/12.28)	...................HF...VPAASQQfrpvgQV...PSSNVGMPAVQNQ...QMQF
  152-  201 (36.70/16.40)	GQPQNnvsassqfqptsQVHAsvaPVAGQPW...........LSSGNQSVSLAIPIQQTGQ
  202-  248 (62.03/33.43)	QPPL...issadtaanaPIHT...PPSASDW.....QE...HTSADGRRYYYNKKTRQSSW
  249-  289 (54.00/28.03)	EKPLE.........lmtPIER...ADASTVW.....KE...FTTPEGRKYYYNKVTKQSKW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.26|      15|      17|     321|     337|       2
---------------------------------------------------------------------------
  332-  347 (17.82/ 7.11)	PAAAIP.vSSNTSQASS
  348-  364 (18.44/13.78)	PVSVTPvaAVANPSPTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.29|      10|      15|     141|     150|       5
---------------------------------------------------------------------------
  141-  150 (18.26/ 8.06)	SSSYSYVPSS
  159-  168 (18.03/ 7.88)	SASSQFQPTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     204.83|      43|      74|     532|     574|       6
---------------------------------------------------------------------------
  472-  506 (45.86/28.48)	.......KQEAKNAFKSLL.E.........SANVQSDWTWEQTMREIINDKR
  532-  574 (72.16/49.26)	AEERRMRQKKAREEFTKMLEE.........SKELTSSMRWSKAQSLFENDER
  604-  651 (53.22/34.30)	AEEKR....RNIAEYRKFLEScdfikvqhfQKRIQANSQWRKVQDRLEDDER
  683-  716 (33.60/18.79)	KEQLRRAERKNRDAFRKLMDE......hvvDGTLTAKTYW............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      47.83|      11|      15|     368|     378|       7
---------------------------------------------------------------------------
  368-  378 (16.18/ 8.14)	STVVPVSQSAA
  386-  396 (16.24/ 8.20)	SPAVAVTPLPA
  401-  411 (15.41/ 7.37)	GSTTPVTSVNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.82|      17|      78|     663|     679|       8
---------------------------------------------------------------------------
  663-  679 (30.44/22.37)	MFQDYIHDLEKEEEEKK
  744-  760 (28.38/20.37)	LFEDVVEELEKQYQQDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.08|      16|      30|      95|     111|      10
---------------------------------------------------------------------------
   95-  111 (27.60/16.84)	APSAQPmHVP.FGQTNRP
  123-  139 (28.48/12.91)	APPLNS.HMPgLGAPGMP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00523 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKK
2) MANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPW
3) SAEMPAAAIPVSSNTSQASSPVSVTPVAAVA
4) SPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYAN
186
1
328
361
242
182
358
471










Molecular Recognition Features






MoRF SequenceStartStop




1) DGRRYYYNKK
2) GRKYYYNK
233
275
242
282