<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00522

Description Pre-mRNA-processing protein 40A isoform 5
SequenceMANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPWLSSGNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKKTRQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYYNKVTKQSKWTIPEELKLAREQAQVVASQGAPSDTGVASQAPVAGAVSSAEMPAAAIPVSSNTSQASSPVSVTPVAAVANPSPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYANKQEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVELERKERENAAEEKRRNIAEYRKFLESCDFIKVQHFQKRIQANSQWRKVQDRLEDDERCSRLEKIDRLVMFQDYIHDLEKEEEEKKKMQKEQLRRAERKNRDAFRKLMDEHVVDGTLTAKTYWRDYCLKVKDLPPYLAVASNTSGSTPKDLFEDVVEELEKQYQQDKTHIKDAMKSGKISMVSTWTVEDFKAAISEDVGSLPISDINLKLVYEELLKSAKEKEEKEAKKRQRLADDFTKLLHTYKEITASSDWEDSRPLFEESQEYRSIAEESLRREIFEEYIAYLQEKAKEKERKREEEKVCEFLAMMSK
Length904
PositionUnknown
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.07
Grand average of hydropathy-0.789
Instability index58.78
Isoelectric point6.27
Molecular weight101257.09
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00522
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     320.98|      38|      38|     216|     253|       1
---------------------------------------------------------------------------
    7-   41 (40.56/16.79)	.......PSSAqPHW.....PPAVGSLGPQSYGSPLSSQFRPVVPMQ
   45-   82 (37.69/15.07)	..HF...VPAA.SQQfrpvgQVPSSNVGMPAVQNQ...QMQFSQPMQ
  100-  127 (44.63/19.22)	PMHV...PFGQ.TN......RPLTSGSP.......QSHQTA..PPLN
  136-  156 (35.21/13.59)	P.GM...PPSS.S.Y.....S...........Y....VPSSFGQPQN
  169-  205 (36.44/14.33)	QVHAsvaPVAG.QPW........LSSGNQSVSLAIPIQQTGQQPPL.
  216-  253 (68.73/33.62)	PIHT...PPSA.SDW.....QEHTSADGRRYYYNKKTRQSSWEKPLE
  257-  294 (57.72/27.04)	PIER...ADAS.TVW.....KEFTTPEGRKYYYNKVTKQSKWTIPEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     143.23|      35|      38|     320|     357|       2
---------------------------------------------------------------------------
  310-  344 (50.36/34.30)	APSD...TGVASQA.PVAGAVSSAEMpaAAIPVSS...NTSQ
  345-  379 (44.04/27.66)	ASSPVSvTPVAAVAnPSPTLVSGSTV....VPVSQ...SAAT
  380-  415 (48.84/26.88)	NASEVQ.SPAVAVT.PL.PAVSSGG...STTPVTSvnaNTTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     507.82|      88|     205|     598|     685|       3
---------------------------------------------------------------------------
  471-  541 (89.19/59.78)	....NKQEAK..N..AFKSLLESAN...........VQSDWTWE....QTMR...EIIN.DKRYGALKTLgERKQAFNEYLGQR.KKLEAEERRMRQKK
  543-  597 (71.06/45.95)	R......E.......EFTKMLEE..........SKELTSSMRWS....KAQS...LFEN.DERFKAVERArDREDLFENYIVEL.ER............
  598-  685 (146.03/103.15)	KERENAAEEKRRNIAEYRKFLESCDFIKVQH.FQKRIQANSQWR....KVQD...RLED.DERCSRLEKI.DRLVMFQDYIHDL.EKEEEEKKKMQKEQ
  689-  766 (84.80/56.43)	AERKN......RD..AFRKLMD.......EHvVDGTLTAKTYWRdyclKVKDlppYLAV.ASNTSGSTPK.D...LFEDVVEEL.EKQYQQDKTHIKDA
  806-  894 (116.74/80.80)	EELLKSAKEKEEKEAKKRQRLAD.DFTKLLH.TYKEITASSDWE....DSRP...LFEEsQEYRSIAEES.LRREIFEEYIAYLqEKAKEKERKREEEK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00522 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNQSVSLAIPIQQTGQQPPLISSADTAANAPIHTPPSASDWQEHTSADGRRYYYNKK
2) MANNSQPSSAQPHWPPAVGSLGPQSYGSPLSSQFRPVVPMQQGQHFVPAASQQFRPVGQVPSSNVGMPAVQNQQMQFSQPMQQFPPRPNQPGLSAPSAQPMHVPFGQTNRPLTSGSPQSHQTAPPLNSHMPGLGAPGMPPSSSYSYVPSSFGQPQNNVSASSQFQPTSQVHASVAPVAGQPW
3) SAEMPAAAIPVSSNTSQASSPVSVTPVAAVA
4) SPTLVSGSTVVPVSQSAATNASEVQSPAVAVTPLPAVSSGGSTTPVTSVNANTTMIRSLESTASQDSVHFTNGASAQDIEEAKKGMATAGKVNVTPVEEKVPDDEPLVYAN
186
1
328
361
242
182
358
471










Molecular Recognition Features






MoRF SequenceStartStop




1) GRKYYYN
2) GRRYYYNK
3) LRREIFEEYIAYLQEKAKE
275
234
867
281
241
885