<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00501

Description WD repeat-containing protein 42A isoform 1
SequenceMDQTPRSVAAAANSRAYQFHPARAAITDLFNLYLGRSSHQKADDSIRELPNKTQKRVLALNRELPPRNEQFLLDFEQLQTQFGDQDQLRSVTESVLISLVIQCCSHAPRAEFLLFALRSLCNIGYINWDTLLPALLSSVSSAEVPAGQGSQGVPSVSTTSLSQSGMMPSTSVITNTSNFQSSNPVSTLTSVHGIGSPAQSTIEPLPGATLSPVKSSDISSNGQPSTTRMNSSIRDNAISSLRQLCCKIILTGLECSLKPVTQAEIFCHMLNWLVNWDQRQQGSEECDGKTWRPDKALIEWLHSCLDVIWLLVEEDKCRVPFYELLRSGLQFIENIPDDEALFTLILEIHRRRDMMAVHMQMLDQHLHCPTFGTHRILSQTTPNVSVEAVANLRYSPITYPSVLGEPLHGEDLAASIQRGSLDWERALRCIRHAIRSTPSPDWWKRVLVVAPCYRGSAQVPTPGAVFTSDMICEATIDRIIELLKLTNSEINCWQEWLVFSDIFFFLMKSGCIDFVDFVDKLGSRLTESDHHILRTNHVTWLLAQIIRVEHVMAALNNDTRKVETTRKILSFHREDRSSDPNNPQSILLDFISSCQNLRIWSLNTTREYLNNEQLQKGKQIDEWWRQVSKGERMMDYMNMDDRSIGMFWVVSYTMAQPAGETVMNWLSSGGATELLSGATVQPNERLMVMQEVSPLPISLLSGFSMNLCLKLVLQLEESLFIGQVVPSIAMVETYTRLLLIAPHSLFRSHFSHLAQRNASLLSKPGVTLLVLEIVNYRLLPLYRYQGKCKTLMYDVTKIISALKGKRGDHRVFRLAENLCINLILSLRDFFSVKREGKGPTEFTETLNRITIITLAITIKTRGIADADHLLYLQTMLEQILATSQHTWSKKTLRHFPPLLRDVLMTRIDKRGLAIQAWQQSETTVINQCTQLLSSSADPNYVMTYIRTSFPQHRQYLCAGAWILMQGHPENINSGNLARVLREFSPEEVTANIYTMVDVLLHHIHMELQHGHSLQDLLLKTCANLAFFVWTHDLIPLDILLLALIDRDDDPHALRIVISLLDRQEFQQRMNLYCLNRNSPEHWLHTAIFKRTDLQKALGNHLSWKDRYPTFFDDIAARLLPVIPLIVYRLIENDATESADRILAMYSPFLAYHPLRFTFVRDILAYFYGHLPGKLIVRILNVLDLRKIPFSESFPQHISSSNPAMCPPLEYFATLLLALVNNVIPPLNSNSRSGSMGDASNNAMRGPHNRTPPTPHSGPANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPISASQIVSSLVQIVVNIQPTLIQSSNGLHGPSSGLGQGSVLPTSPSGGSTDSLSAGRSTPSVSGINTSSFVSRSGYTCQQLSCLFIQACGLLLAQLPREFHLQLYMEASRIIKESWWLTDGQRSPGELDSAVSYALLDPTWASQDNTSTAIGNIVALLHAFFSNLPQEWLEGTHDIIKHLRPVTSVAMLRIAFRIMGPLLPRLANAHNLFNKILSLLLNILVDVFGKNCQPPVPVDASEIMDLIDYLHHVIHYEGQGGPVQASSKPRPEVLALCGRAAESLRPDVQHLLSHLKTDINSSIYAATHPKLVQNPS
Length1606
PositionTail
OrganismTheobroma cacao (Cacao) (Cocoa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Byttnerioideae> Theobroma.
Aromaticity0.07
Grand average of hydropathy-0.074
Instability index47.29
Isoelectric point6.59
Molecular weight180177.95
Publications
PubMed=23731509

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00501
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     486.37|     157|     182|     265|     446|       1
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  154-  368 (178.08/199.38)	PSVSTTS.LSQSgmMPSTSViTNTSNFQSSnPVsTLTSVhgIGspaqstieplpgatlSPVKSSDISSngqpsttrmnsSIR..D.NAISSLRQLCCkiILTGLECSLKP.....V..............tqaeIF.CHMLnwlvnwdqrqqgseeCDGKTWRPDKaLIEWLHS...CLDvIWlLVEEDkcrvPFYELLRSG.LQFIENIpddEALFTLILE....IHRRRDMMAVHMQMLD.QHLHC
  369-  553 (241.18/182.54)	PTFGTHRILSQT..TPNVSV.EAVANLRYS.PI.TYPSV..LG...............EPLHGEDLAA...........SIQ..R.GSLDWERALRC..IRHAIRSTPSPDWWKRVlvvapcyrgsaqvptpgaVFtSDMI...............CEATIDRIIE.LLKLTNSeinCWQ.EW.LVFSD....IFFFLMKSGcIDFVDFV...DKLGSRLTEsdhhILRTNHVTWLLAQIIRvEHVMA
  554-  627 (67.11/35.68)	ALNNDTRKVETT..RKILSF.HR.EDRSSD.PN.NPQSI..L..................L...DFIS...........SCQnlRiWSLNTTREYLN..NEQLQKGKQIDEWWRQV....................................................................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     283.79|      96|     182|     893|    1045|       2
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  893- 1019 (141.93/156.61)	RHFPP.LLRDVLMTRID.KRGLAIQ.AWQQSETTVINQ.CTQLLSSSadPNYVMTYIrtsfpqhrqylcagawilmqghpENINSGNLARVLREFSPEEVTANI.YTMV.DVLLHHihmelqHGHSLQDLLLK
 1076- 1177 (141.86/124.62)	RNSPEhWLHTAIFKRTDlQKALGNHlSWKDRYPTFFDDiAARLLPVI..PLIVYRLI.......................ENDATESADRILAMYSPFLAYHPLrFTFVrDILAYF......YGHLPGKLIVR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.17|      44|     624|     826|     869|       3
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  826-  869 (73.42/42.63)	LRDFFSVKREG..KGPTEFTETLNRITIIT.LAITIKTRG.....IADADHL
 1451- 1502 (60.74/34.12)	LHAFFSNLPQEwlEGTHDIIKHLRPVTSVAmLRIAFRIMGpllprLANAHNL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     249.52|      81|    1135|      61|     150|       4
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   61-  150 (117.80/115.61)	NReLPPRNEQFLLDFEQLQTQFGD.QDQlRSVTESVLISLVIQCCSHAPRAEFLlfaLRSLCNIgYINwdtLLPALLSSVSSAEVPA...GQGS
 1248- 1332 (131.73/93.78)	NR.TPPTPHSGPANASEGQKAFYQiQDP.GTYTQLVLETAVIEILSLPISASQI...VSSLVQI.VVN...IQPTLIQSSNGLHGPSsglGQGS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.34|      23|     349|    1020|    1063|       6
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 1021- 1061 (24.72/56.14)	CANLAFFvwthdliplDILLLALIDRdddphalriVISLLD
 1205- 1227 (43.62/18.90)	CPPLEYF.........ATLLLALVNN.........VIPPLN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.98|      39|    1504|      21|      60|       7
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   21-   60 (61.61/46.30)	PARAA.ITDLFNlYLGRSSHQKADDSIRELPNKTQKRVLAL
 1527- 1566 (65.37/44.55)	PVDASeIMDLID.YLHHVIHYEGQGGPVQASSKPRPEVLAL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00501 with Med23 domain of Kingdom Viridiplantae
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