<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00447

Description Uncharacterized protein
SequenceMTTASATPQQMRDRLLQAIDSHSNQICNMVAVLEVITYLEKFPITKEALEETRLGKLINDVRKQTKDEDLAKRAKKLLRSWQKLIEPGQNETPSRGAMCVPGSANGSAHPLRTDIPPPDVSMASKGVPEVKTRNDVHNTHSPKAEKSSSRKRRGEQRDSVHLVAKISNLSPYEQMYNTPPPPTNGIAGSPEAPPSPDRARTEPLENDKHSRIPQQARLDEGGGGQYQAKSPHCLSSSLRSPRAMKQEMMASLHWPGSSEVTTHPPRNAATLEPPSCSELHRPTPSSSVVVVKAEAEVAASSSDRKKRKKYRSRDYSVNLQGQDTEDQTRPVRLKERRLTFDPVTGQIKSMVHKEPSQVEEPPRPPPPEPQQRTHLPLQQHPAPTPSPFQQTNWKELSRNDIIQSYLNLQSNVLTSSGVQAPGAHFFMSEYLKREESDVREARRGVHVLQLDSLVTDTPGVSREVTDEDLHRVHMEHWQGVNGCCDTKGTWYDWTECISLDPHGDESKLNILPYVCLD
Length517
PositionUnknown
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.04
Grand average of hydropathy-0.885
Instability index63.02
Isoelectric point8.05
Molecular weight57844.28
Publications
PubMed=24755649

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00447
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     227.67|      57|      62|     116|     172|       1
---------------------------------------------------------------------------
  116-  164 (77.19/28.23)	..............PPPDVSMASKGVP...........EVKTRNDVHNTH.SPKAEKSS...SRKRRGE......QRD.SVHLVA
  165-  235 (80.14/29.55)	KISNLSPYeqmyntPPPPTNGIA.GSP...........EAPPSPDRARTE.PLENDKHSripQQARLDEggggqyQAK.SPHCLS
  272-  319 (29.33/ 6.93)	..............EPPSCSELHRPTPsssvvvvkaeaEV..............AASSS...DRKKRKK....yrSRDySVNL..
  346-  378 (41.01/12.13)	QIKSMVHK......EPSQVEEPPRP...............PPPEPQQRTHlPLQ...............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.16|      27|     396|      53|      82|       2
---------------------------------------------------------------------------
   53-   82 (37.87/33.51)	RLGKLIND...VRKQTKDEDLaKRAKklLRSWQ
  449-  478 (44.29/27.82)	QLDSLVTDtpgVSREVTDEDL.HRVH..MEHWQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00447 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) WQKLIEPGQNETPSRGAMCVPGSANGSAHPLRTDIPPPDVSMASKGVPEVKTRNDVHNTHSPKAEKSSSRKRRGEQRDSVHLVAKISNLSPYEQMYNTPPPPTNGIAGSPEAPPSPDRARTEPLENDKHSRIPQQARLDEGGGGQYQAKSPHCLSSSLRSPRAMKQEMMASLHWPGSSEVTTHPPRNAATLEPPSCSELHRPTPSSSVVVVKAEAEVAASSSDRKKRKKYRSRDYSVNLQGQDTEDQTRPVRLKERRLTFDPVTGQIKSMVHKEPSQVEEPPRPPPPEPQQRTHLPLQQHPAPTPSPFQQTNWK
81
394










Molecular Recognition Features






MoRF SequenceStartStop




NANANA