<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00446

Description Uncharacterized protein (Fragment)
SequenceYILLVLFLCICFVHNIDLSHLSLTHPFSLSLSLGLPLSHSLSLSWSLFLALLLSFSLPVSQGEDGAAGLSDDAARAAAHARTASTSLIHETDLAVSINDLDNLFNSDEDELTPGSRRAVNGTGDKFGNKEPKPATLDPVSCISSADLHQMFPTPPSLEQHIMGYSPMNMGSKEYGGLEVGQGMTNLDGTSSLGGHFKIEVEEGYCSPKPQEIKDFSFVYKPELCQAFVGCSMFAPLKTLPSQCLPPIKMPDECIYRPSWTTVGKQEMLNHPHVPSMAYLNKDSNIPSVGSAMDQDYSQSYTPQTHTPFMSNSAPPSNSGTGILPSPATPRFSAPTPRTPRTPRTPRGPASVQGSLKYENSDLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVTLILSESVMNLFKDCNFDSCCICVCNMNIKGADVGVYLSDPTGEAQYPCTCGFSAVVNRRYGNGSGLFLEDELDIIGRDSDVSREAEKRFEALRQHSLERTGGGGRGERVPDELILLLQDQCTNPFSPMAGMEPDSLAARGPGGCPVPACVRVEERDFHSDCYMALEHGRQFMDNMSGGKVDEALVKSTCLHRWSKQNAVDISALCSQDVLRVLLSLQPVLQDAIQKKRTVRSWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLVGFEYDFVVLSPFGLPYWEKLLLDPFGSHRDVGYLVVCPDNEALLQGAKNFFRDLTAVYEVRLENVTTLMSMDHARDGASLES
Length746
PositionMiddle
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.08
Grand average of hydropathy-0.227
Instability index46.62
Isoelectric point5.10
Molecular weight81377.23
Publications
PubMed=24755649

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00446
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     165.66|      35|     211|     294|     330|       1
---------------------------------------------------------------------------
  255-  290 (37.74/12.34)	YRPSWTtvgkqemlnhP..HVPSMAYLNKDS..N....I.PSVGS..
  296-  330 (70.55/31.60)	YSQSYT..........PQTHTPFMSNSAPPS..NSGTGILPSPATPR
  363-  380 (23.95/ 6.62)	YSPAST..........PSTCRPL..NSVEP.................
  522-  546 (33.42/12.15)	.....................P.MAGMEPDSlaARGPGGCPVPACVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.43|      16|      17|      28|      44|       2
---------------------------------------------------------------------------
    4-   19 (28.00/12.33)	LVLFLCICFVHNIDLS
   29-   44 (27.29/16.80)	LSLSLGLPLSHSLSLS
   46-   60 (20.13/ 9.09)	.SLFLALLLSFSLPVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.80|      21|     136|     419|     445|       4
---------------------------------------------------------------------------
  419-  440 (34.86/35.99)	CNMNIkGADVGVYL..........SDPTGEAQ
  451-  481 (28.95/10.84)	VNRRY.GNGSGLFLedeldiigrdSDVSREAE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00446 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SVGSAMDQDYSQSYTPQTHTPFMSNSAPPSNSGTGILPSPATPRFSAPTPRTPRTPRTPRGPASVQGSLKYENS
287
360










Molecular Recognition Features






MoRF SequenceStartStop




NANANA