<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00420

Description Uncharacterized protein
SequenceMYLTPCGPVPLPRIPPSKGVGEETRQALERSLLDCTFRLQGRNNRTWVGELVLANCPLNSTHSKEQASTRHVYLTYENPLSEPVGGRKLVEMFLNDWSAISQLYQCVLVFSRSLPEMPSYLSLFSEIRLYNYRKLVLCYGSTKGSSVTIQWNSSTQRFHLSLGTVGPNSGCSNCHNIILHQLQEMFNKTPTVVQLLQVLSDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSPTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNTKIVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPVGGDIMDTLMSQFQAQQQQTMRGGPGGVYPPLTSPPTPYHPNVAPSPSMMPTQSPGTIHASGSPSGALRAPSPFGPTPSPSSLGIAMGPTSFASPHGALDPSSPYAMVSPSQRGQWPGSPQVSGPSPGARIHGMSPGNPSLHSPIPDASHSPRTGSSSGAIPSSMPPPRKLPQRSWAASIPTILTHNALHVLLLPSPTPCLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQLEPNLSIVNSNEPGVIMFKTEVLKCRVALNPKTYQTLQLKVTPENAGPWSQEELQVLEKFFETRVAGPPFKYNTLNAFTKLLGAPTNILRDCVRIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTIAVVLKSKMLFFLQLTQRLPVPQEPVNIIVPIVYDMATGLTQQADIPRQHSSSGAAALMVSNILKRFNELHPARQGECTIFASVHELMVNLNLPPGGRQ
Length775
PositionTail
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.07
Grand average of hydropathy-0.184
Instability index60.56
Isoelectric point9.27
Molecular weight84741.69
Publications
PubMed=24755649

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00420
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     200.71|      29|      32|     350|     378|       1
---------------------------------------------------------------------------
  312-  339 (31.76/ 8.30)	PSPVGGDIMDT..L.....MsqF.........QA..QQQQTMR..GGP
  350-  378 (57.32/19.98)	PTPYHPNVAPS.PS.....M..M.........PT..QSPGTIHASGSP
  385-  415 (41.79/12.88)	PSPFGP..TPS.PSslgiaM..G.........PT...SFASPHGALDP
  416-  440 (40.81/12.43)	SSPY.AMVSPS.Q...................RG..QWPGSPQVSGPS
  441-  481 (29.03/ 7.05)	PGARIHGMSPGnPS.....L..HspipdashsPRtgSSSGAIPSSMPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.94|      35|      37|     546|     582|       2
---------------------------------------------------------------------------
  546-  582 (56.77/34.43)	QLE..PNLSIVNSNEPGVIMFKteVLKCRVALNPKTYQT
  584-  620 (59.17/30.84)	QLKvtPENAGPWSQEELQVLEK..FFETRVAGPPFKYNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.74|      34|     506|     194|     229|       4
---------------------------------------------------------------------------
  194-  229 (55.79/38.97)	QLLQVLSDTQAPLNAInkLPTV.PM.LGLTQRTNTAYQ
  690-  725 (53.96/31.66)	QLTQRLPVPQEPVNII..VPIVyDMaTGLTQQADIPRQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00420 with Med14 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NQDARRRSVNEDDNPPSPVGGDIMDTLMSQFQAQQQQTMRGGPGGVYPPLTSPPTPYHPNVAPSPSMMPTQSPGTIHASGSPSGALRAPSPFGPTPSPSSLGIAMGPTSFASPHGALDPSSPYAMVSPSQRGQWPGSPQVSGPSPGARIHGMSPGNPSLHSPIPDASHSPRTGSSSGAIPSSMPPPRKLP
297
486










Molecular Recognition Features






MoRF SequenceStartStop




NANANA