<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00409

Description Uncharacterized protein
SequenceMMAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPSKISSNFSSIIAEKLRYNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRSAWMIKMTCAYHAAITETKVKKRHVIDPCIEWTQIITKYLWEQLQKVAEFYRQSPSQGCGSPLPANPAEVDTAMKQWEYNEKLAMFMFQVGWSFGLSVVFCCLFACLSQVPRLSPPGTYVPAISDAFEKQNKFASVGRA
Length295
PositionKinase
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.12
Grand average of hydropathy-0.392
Instability index46.22
Isoelectric point9.37
Molecular weight33377.04
Publications
PubMed=24755649

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00409
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.41|      20|     247|      18|      37|       2
---------------------------------------------------------------------------
   18-   37 (39.96/21.12)	PRLGPPDVY.P..QDPKQKEDEL
  267-  289 (30.45/14.69)	PRLSPPGTYvPaiSDAFEKQNKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.84|      21|      37|     139|     159|       3
---------------------------------------------------------------------------
  139-  159 (36.94/23.21)	KKEEVFGYLAKYTVPVMRSAW
  177-  197 (39.89/25.55)	KKRHVIDPCIEWTQIITKYLW
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00409 with Med12 domain of Kingdom Metazoa

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