<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00402

Description Uncharacterized protein
SequenceMMAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPSKISSNFSSIIAEKLRYNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRSAWMIKMTCAYHAAITETKVKKRHVIDPCIEWTQIITKYLWEQLQKVAEFYRQSPSQGCGSPLPATSAEVDTAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECSEKVRPGEDELLKLLLPLLLQYLGEFVQSAYLSRRLAYFCTRRLNLLLSDGSLGPGAGGHPAHSILAQPGNALPPMPTSQPAGGNQPQTSFTDFYICPQHRPLVFGLSCMLQSIMLCCPSALVWHYSLTDSRNKTGSPLDLLPISPSNLPMPGGNGTFTQQVRAKVREIEEQVKDRGQAVEFRWSFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQNKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQAEIEAESSQRCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVLTEPSNESERVEFSNQVLLFCELIRHDVFSHNIYMCTLISRGDLASDSHLPRPRSPSDEPSDESESKEAGSSVKNEACYVEAAAVILLCMMNHPTFTFESFSRCCYPEQFTGEIRVKSLAHGHIDRFFT
Length718
PositionKinase
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.09
Grand average of hydropathy-0.364
Instability index55.47
Isoelectric point6.13
Molecular weight80565.73
Publications
PubMed=24755649

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00402
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.81|      17|      67|     330|     354|       1
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  330-  354 (26.10/35.08)	PGNALP......PMPtsqpaGGNqpqTSFTD
  399-  421 (30.71/17.03)	PLDLLPispsnlPMP.....GGN...GTFTQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.65|      13|      34|     197|     209|       2
---------------------------------------------------------------------------
  197-  209 (25.11/17.59)	WEQLQKVAEFYRQ
  233-  245 (26.53/18.99)	WEYNEKLAMFMFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.79|      11|     346|     212|     227|       3
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  212-  227 (15.81/21.08)	SQGCGsplpaTSAEVD
  547-  557 (20.98/11.51)	SQRCG.....ESEVVD
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.62|      29|      69|     595|     625|       4
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  595-  625 (45.53/46.70)	NESER.............VEfSNQVLLFCeLIRHDVFSHNIY.MC
  651-  693 (40.09/29.55)	DESESkeagssvkneacyVE.AAAVILLC.MMNHPTFTFESFsRC
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00402 with Med12 domain of Kingdom Metazoa

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