<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00396

Description Uncharacterized protein
SequenceMVAVMDVISYLEKYPITKEALEETRLGKLINDVRKKTKDEDLVKRAKKLLRTWQKLIEPGQSEAQSKGHRGPPGAANGANNPCRTAVSPPAAIPPSDKMVSELKSRNDFNNYYSPKAEKSGNRKRKGEQRDGQHLPAKISKKTAYERTRNSRLPINGIGASPKAFMDTLDAYSHPKSDKDGADHLDNDRLNKIPINAVKPHPSSPGLAKPPSTSALLKTAVLQQQAKMDLVASGRGQHQPKSPHRNSYSPRSTKQDVVVKLSAPKATTLLSPAQSPRVMDSSGLEPSSLPSPQPLTSCIQGSLTDGQADVDQRLQHSTMRPDSLHNSKATSRSKVKAEGNGAATSTVRKRNKYRSRDYTVNLGGQPTEESTKPCRLKDRRLTFDPVTGQIKSWTHKESYPEWEATVVPVTPEPRTELLKRNQYAQNTPVTPSPFQQTNWKELSRNEIIQSYLNRQSNVLMSSGAQTSGAHLFMNEYMEHHIKEARKTHVLVPNIPDMDLPGVSREVINEDLDRIHKEHWPGVNGCHDTKDNWYDWTECISLEPHGDESKLNILPYVCLD
Length559
PositionUnknown
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.05
Grand average of hydropathy-0.901
Instability index53.72
Isoelectric point9.44
Molecular weight62356.55
Publications
PubMed=24755649

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00396
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.95|      42|      76|     136|     179|       1
---------------------------------------------------------------------------
   90-  117 (27.01/12.44)	..................PAAIppSDKMVS......ElKSRND...FNNY.YSPKA
  118-  164 (65.15/38.87)	EKSGNRKRKGEQRdgqhlPAKI..SKKTAY......E.RTRNSRLPINGIGASPKA
  167-  202 (38.79/25.75)	DTLDAYSHPKSDK.................dgadhlD.NDRLNKIPINAVKPHP..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.46|      18|      21|     408|     425|       2
---------------------------------------------------------------------------
  408-  425 (34.00/23.44)	PVTPEPRTEL....LKRNQYAQ
  428-  449 (28.46/18.32)	PVTPSPFQQTnwkeLSRNEIIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     184.69|      58|      77|     235|     294|       3
---------------------------------------------------------------------------
  235-  294 (92.03/54.72)	RGQHQPKSPHrNSYSPRSTKQDVVVKLSAPKATTLLSPAQSPRVMDSS...GLEPSSlPSPQP
  313-  373 (92.66/47.89)	RLQHSTMRPD.SLHNSKATSRSKVKAEGNGAATSTVRKRNKYRSRDYTvnlGGQPTE.ESTKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00396 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EWEATVVPVTPEPRTELLKRNQYAQNTPVTPSPFQQTNW
2) WQKLIEPGQSEAQSKGHRGPPGAANGANNPCRTAVSPPAAIPPSDKMVSELKSRNDFNNYYSPKAEKSGNRKRKGEQRDGQHLPAKISKKTAYERTRNSRLPINGIGASPKAFMDTLDAYSHPKSDKDGADHLDNDRLNKIPINAVKPHPSSPGLAKPPSTSALLKTAVLQQQAKMDLVASGRGQHQPKSPHRNSYSPRSTKQDVVVKLSAPKATTLLSPAQSPRVMDSSGLEPSSLPSPQPLTSCIQGSLTDGQADVDQRLQHSTMRPDSLHNSKATSRSKVKAEGNGAATSTVRKRNKYRSRDYTVNLGGQPTEESTKPCRLKDRRL
401
53
439
381










Molecular Recognition Features






MoRF SequenceStartStop




1) LLRTWQKLIE
49
58