<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00391

Description Uncharacterized protein
SequenceMDLQNKDILPREILPVVVIGNGPSGICLSYLLSGYTPYLSPEGTHPNPLLQGKLDQQPHLSLLELDLEYLCEGLEGRSSNPVAVLFDSLLLPDSDFGLDHASPLLWRYEPERATPHLVLGKGPPGGAWHAMEGSMLTLSLANWMELPGLKLKEWMREKRRNVRNDRATPAEIASYYQHYVNQMGLEDSFACGTTVTSIQRVNCEGASSRSFWKVQGTQKREADELGEGSLSEVPFIVCADYVVLATGTHDIPARLGVEGEGLPFVCHSFWELEAAISKGQLDHTSDPVLVVGAGLTAADAVLAAHHLNTPVYHAFRRSVTDPGLIFNQLPKLLYPEYHKVHQMMTQQQQHGQDTPSSGGTGTLATSACPNTGWWPSSLTGSACWRGRTDVAPCCRSPWPCSFSTWKMDSGIEKECSALGGLFQIIMNDMKASYPAWEDFVTKGVKLQSQLRTTIVVTGSFLEAFQKVADMATGTRGATKEIGSALTRMCMRHRSIESKLKLFTTALTDTLINPLELKIEEWKKVASQLDKDHAKEYKKARADIKKKSSDTIKLQKKVKKGKDEVRGQLDSALQDVNVRYAVLEETEKRAACRALIEERGRYCSFVSMLKPVLDHEISMLGEVTHLQTILEDLSTLTAEPSKLPPASEQVILDLKGSDYSYSYQTPPASPSNTLSRTSSISGNYNSVRHVPSLDSITSSLDGIHLRPPSMESAQVTHTAEVSGSWSGHTGSGTENGTAMPPPHNSYTQHGERARALSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSEDTIPSHDYDYICLHRGEEEHHGPPDFDKSSTIPRNSDLSLQYRKMFQSKRPASTVSLLAEPELLGLCQSHTATIRRKPSSKPAYRRGTISGGMPIPICTPQVPLKALGVEKGGGNCGGGGNSGSNENMGPPEGGMGMSWKVDHGLVHTKHSLCTSTQSLSAMPLHHSSSTSPYYSLIPGQAPVPMGSSEQLYQLSKQQQYALHQQQQKQYQQQHLQYQQQPQTHQVQPTAQTQQQQQTFQLQQRFQQQQLQQQQLYQQQLQQQQQQKLQHQKQLQQQQLIQQQQQPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAEEPSDAGGHMVAMIRGVKLRRTLTNDRSAPFIPPPSHFK
Length1170
PositionTail
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.06
Grand average of hydropathy-0.576
Instability index55.49
Isoelectric point6.72
Molecular weight128931.65
Publications
PubMed=24755649

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
actin binding	GO:0003779	IEA:InterPro

GO - Biological Process
plasma membrane organization	GO:0007009	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00391
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     115.55|      18|      18|    1051|    1068|       1
---------------------------------------------------------------------------
 1006- 1024 (30.88/11.72)	ALHQQ.QQKQYQ.QQHLqYQQ
 1046- 1063 (27.46/ 9.68)	.LQQRfQQQQLQ.QQQL.YQQ
 1064- 1082 (30.73/11.63)	QLQQQ.QQQKLQhQKQL.QQQ
 1083- 1096 (26.49/ 9.10)	QLIQQ.QQQPIQ.QQ.....S
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.90|      52|      56|     200|     252|       2
---------------------------------------------------------------------------
  200-  252 (86.69/57.34)	RVNCEGAS....SRSFWKVQGT.QKREADELGEGSLSEVPFIVCADyVVLATGTHDIP
  254-  310 (80.21/48.03)	RLGVEGEGlpfvCHSFWELEAAiSKGQLDHTSDPVLVVGAGLTAAD.AVLAAHHLNTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.99|      18|      19|     628|     646|       3
---------------------------------------------------------------------------
  628-  646 (27.50/22.75)	ILeDLSTLTAEPS.KLPPAS
  650-  668 (29.49/18.93)	IL.DLKGSDYSYSyQTPPAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.76|      19|      19|     676|     694|       4
---------------------------------------------------------------------------
  676-  694 (34.55/20.50)	TSSISGNYNSVRHVPSLDS
  696-  711 (29.42/16.32)	TSSLDGIH..LRP.PSMES
  717-  730 (19.79/ 8.48)	TAEVSGSWSG..HTGS...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.53|      17|      19|     752|     768|       5
---------------------------------------------------------------------------
  752-  768 (28.11/17.64)	ARALS...TSGKPQSAREQL
  769-  788 (23.43/13.26)	ALALGgglNSEAPRTSHDSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.85|      13|      19|     915|     927|       9
---------------------------------------------------------------------------
  915-  927 (26.81/13.93)	EKGGGNCGGGGNS
  931-  943 (27.04/14.12)	ENMGPPEGGMGMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.17|      20|      30|     790|     809|      10
---------------------------------------------------------------------------
  790-  809 (37.73/19.53)	C.SSGYSTQTTTPSCSE.DTIP
  817-  838 (31.45/15.06)	ClHRGEEEHHGPPDFDKsSTIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.37|      18|      30|     401|     418|      11
---------------------------------------------------------------------------
  384-  398 (18.98/ 8.35)	....WR..GRTDVAPCCrSPW
  401-  418 (31.94/19.30)	SFSTWK..MDSGIEKEC.SAL
  432-  450 (24.46/12.98)	SYPAWEdfVTKGV.KLQ.SQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.39|      12|      15|     974|     985|      12
---------------------------------------------------------------------------
  974-  985 (22.25/11.21)	STSPYYSLIPGQ
  992- 1003 (20.14/ 9.48)	SSEQLYQLSKQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.85|      10|      26|     312|     321|      13
---------------------------------------------------------------------------
  312-  321 (18.10/ 9.92)	YHAFRRSVTD
  337-  346 (19.75/11.45)	YHKVHQMMTQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00391 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYICLHRGEEEHHGPPDFDKSSTIPRNSDLSLQYRKMF
2) GVEKGGGNCGGGGNSGSNENMGPPEGGMGMSWKV
3) QPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAEEPSDAGGHMVAMIRGVKLRRTLTNDRSAPFIPPPSHFK
4) SITSSLDGIHLRPPSMESAQVTHTAEVSGSWSGHTGSGTENGTAMPPPHNSYTQHGERARALSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSE
814
913
1090
694
851
946
1170
805










Molecular Recognition Features






MoRF SequenceStartStop




NANANA