<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00390

Description Uncharacterized protein
SequenceMTSATATPQEMRDRLMQAIDGQSNQICNMVAVMEVISYLEKYPITKEALEETRLGKLINDVRKKTKDEDLAKRAKKLLRTWQKLIEPGQSEALSKGHMGPPGVANAAIPPSGKMVPELKSRNDFNNRYSPKAEKSGNRKRKGEQRDRQHIPMKMSKITAYERTHNSRLPTNGIGASPEAFTDTCGPHLKSDKDGAEHLDIDRLNNIPVNAVKPHPSSPGVPKPPSTSTLLKTAVLQQHGKMDLAVSGGGLHQPKHPRSNSYSPRSTKQDAVVKLSMTKSTTLLSPARSPRIMDSSGLGPSPLRSPHLLTPCMQGSLTVGPLPTESVLHWDGPADVKAESDGSVTSTERKRRKKYRSRDYTVNLSGQPTEETTMPCRLKDRRLTFDPVTGQIKPSTLKESYPEWEATVTPVTPELPRTELLKQNHCAQNSPVTPSPFQQTNWKELSRNEIIQSYLNRQSNVLTLSGAQTSGAHFFMSEYLKQEGHHIKEGRKKHMLVPNIPDTDLPGLSRAVTNEDLNRIHKEHWPGVNGCYDTKDNWYEWTDCISLDSHGDDGKLNILPYVCLD
Length564
PositionUnknown
OrganismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Oncorhynchus.
Aromaticity0.05
Grand average of hydropathy-0.810
Instability index51.73
Isoelectric point9.25
Molecular weight62850.55
Publications
PubMed=24755649

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00390
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.31|      16|      18|     284|     299|       1
---------------------------------------------------------------------------
  284-  299 (31.52/15.58)	SPARSPRIM.....DSSGLGP
  300-  320 (24.79/10.94)	SPLRSPHLLtpcmqGSLTVGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.71|      21|      21|     377|     397|       2
---------------------------------------------------------------------------
  355-  374 (21.53/11.22)	.RSRDYTVN.LSGQpTEETT..MP
  377-  397 (35.51/23.82)	LKDRRLTFDPVTGQ.IKPST..LK
  400-  421 (30.67/19.46)	YPEWEATVTPVTPE.L.PRTelLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.39|      33|      90|     229|     261|       3
---------------------------------------------------------------------------
  229-  261 (58.29/47.07)	LLKTAVLQQHGKMDL.AVSGGGLHQPKHPRSNSY
  321-  354 (53.09/42.07)	LPTESVLHWDGPADVkAESDGSVTSTERKRRKKY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00390 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GPLPTESVLHWDGPADVKAESDGSVTSTERKRRKKYRSRDYTVNLSGQPTEETTMPCRLKDRRLTF
2) IEPGQSEALSKGHMGPPGVANAAIPPSGKMVPELKSRNDFNNRYSPKAEKSGNRKRKGEQRDRQHIPMKMSKITAYERTHNSRLPTNGIGASPEAFTDTCGPHLKSDKDGAEHLDIDRLNNIPVNAVKPHPSSPGVPKPPSTSTLLKTAVLQQHGKMDLAVSGGGLHQPKHPRSNSYSPRSTKQDAVVKLSMTKSTTLLSPARSPRIMDSSGLGPSPLRSPHLLTPCMQGSLT
3) PSTLKESYPEWEATVTPVTPELPRTELLKQNHCAQNSPVTPSPFQQTNW
319
85
393
384
317
441

Molecular Recognition Features

MoRF SequenceStartStop
NANANA