<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00375

Description Uncharacterized protein
SequenceMGKGDKEPAPLYELRPPEWLPRTHVSGDIGYLGFFPPHPSDIEEKLTSKSVTDGLVLPVLVNAEHYSHQHEIRKRLMHEDALGALEDVMNQIFARKAESVASIPQSSFRLPSRVTLNDAKRQAWFADLANPDIPLSKLGKNVPHGAKGHDLLDLLHTNDVAIPRAVWFLRVFGANETAGLRNKPTYNPTQYSVEWANVMTSYMKKQLGEIALPSPPRLVASIKQTFKGVLSDADMRKKWVSRFTYCRALTRPFIEACLTRFMEIEGSSAKEFLPNTSNILRNLITRAFAALPEACISPRIHVQYGAMLEEILMDNFVVENADTASQQNLQGLRQIVVDTLADVQKRNEAMLFQHLPPRVLGSLSSALSDIKLLNSISGKTDMSTVSLFDENSEFSPSFSRKLDFLLTWSVTPLQYGDHRPYAAACLLMLWRNKAEERALRRDAPSPDGQIQDLLFEWLDNSDVAGDPGNLPAVALLFGQLVKHGLFSYGLYMQRLISRGETGLSFTDTEGSRHRQFLRWIPLHSSDTSLISQRKMILYGFRVRETPEDVNEREIRKEFRALLPELFGGSQLAFIPVATLELTSCDRLLSAPRYEQLKTIKQWLLPLYKRFLISHTEPLYETEGLILRVFTLSTIIMARVRSYGSILDMSLCTLEYAHSSPLLTAVIETIRQHIEVWACMNRMQDVATALWAVHQTWRARGSQNRVLLKLLAEVDNDRYLEPAAREQMLSDISAFSHALFPSNENPDTVPPVLPEILLLATDPNPESPSLLANSLWYKYMTSPDWAWKVWDNTVASLRQIPLMMEDIPGRRACALRYATFLLHVDQHLPRGFDEQIRSWFLGSGRNEVAALTPDAWDVVTVVMLYLICYGALTTTTILESLVYPVWQAGASVTSEEQALSLETLLTSVNTLFEHLLLRDECGTGLPPVDVFEAQGLQSRRRDVFREPHFSTLVTNFPALVLIEQNRYLPEPLRVASMTLRRTICRVNVFRQGIYRDLDAVRLTFEKLLESQNVPDELHEPLVSALRLMLNDPGQDGPVNAAEWSSASSLLSPWKLAATSIEIRLTIKQLGEGMARESTRLAACASLDKLTTAVFYHCKSPEEADFVAEMITDVDKTVAGKVREFSFDIFREMDSGNKVESTTRLVNCAGEILRLLANIVAPFRKEKALPPLDQAVQDHLFSALCAKITEMTEFMMGLLQQPWSEDVSCGTQAVIFLARLLQFYLGFQLTWSQQSKDLGEELCANLTRLALIHGAGEGLNLLAFPLIMDTLCYTLDEIPIDMKATVPYDPFRNHPEFNLSDLPSDMPPEYKERLRTMLPYVALNPAVEDLVYATRDASGAIVSAVPVQNRPWEWTEYLGDVPGAEPRGGAEERRGDDDRPTVKNSASLSLELFEARLTGDRVIPAEGYTLKDDLMAEENLRALQDDLSAEGAFRRDWRETRVSLNDAPTAPNVRPSRGTEQEDNIPPLPGFGAHATAASDGRPSSRRPSPASSVRSAASGQLGSATSLRQSPAHPLSRLSVSTTGDVIDVDAFDAGTSASGSTNKRKAMSSIAEHEDIEIVDGPGTAASRASKRTKAKTASKTTAKGRKK
Length1588
PositionKinase
OrganismPycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporaceae> Trametes.
Aromaticity0.08
Grand average of hydropathy-0.222
Instability index50.19
Isoelectric point5.69
Molecular weight177369.34
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00375
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.13|      42|      60|    1146|    1204|       1
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 1146- 1190 (59.69/73.79)	CAGEILRLLANIVaPFRKEKALPPLDQAvQDhLFSALCAKITEMT
 1207- 1248 (71.44/39.00)	CGTQAVIFLARLL.QFYLGFQLTWSQQS.KD.LGEELCANLTRLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     164.45|      52|      59|    1257|    1313|       2
---------------------------------------------------------------------------
 1257- 1313 (83.24/58.59)	LNLLAF.PLIMDtLCYTLDEIPidmKATVPYDPFRNHP....EFnLSDLPSDMPPEYKERLR
 1316- 1372 (81.21/42.88)	LPYVALnPAVED.LVYATRDAS...GAIVSAVPVQNRPwewtEY.LGDVPGAEPRGGAEERR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.00|      15|      60|    1469|    1485|       3
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 1469- 1483 (26.13/16.21)	FGAHATAASDGRPSS
 1488- 1502 (21.86/ 6.00)	PASSVRSAASGQLGS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     417.55|     140|     247|     561|     721|       9
---------------------------------------------------------------------------
  561-  721 (202.88/190.80)	LLPELFGGSQLAFIPVATLeLTSCDRLLsAPRYEQlkTIKQWLLPLYKRflishteplyETEGLILRVFTLSTIIMARVRSYGSIL...............DMSLCTLEYAHSSPLLTAVIETIRQHIevwacMNRmQDVATALWAVhQTWRARGSQNR...........VL...LKLLAEVDNDRYL.EP
  801-  970 (214.66/143.30)	LMMEDIPGRRACALRYATF.LLHVDQHL.PRGFDE..QIRSWFLGSGRN..........EVAALTPDAWDVVTVVMLYLICYGALTtttileslvypvwqaGASVTSEEQALSLETLLTSVNTLFEHL.....LLR.DECGTGLPPV.DVFEAQGLQSRrrdvfrephfsTLvtnFPALVLIEQNRYLpEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.74|      16|     281|     454|     476|      12
---------------------------------------------------------------------------
   18-   36 (28.68/10.27)	EWLPRTHVSGDIGYLgffP
  456-  471 (33.05/22.07)	EWLDNSDVAGDPGNL...P
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.19|      12|     605|     418|     429|      13
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  418-  429 (24.56/13.80)	HRPYAAACLLML
 1017- 1028 (20.63/10.43)	HEPLVSALRLML
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.99|      16|     281|      69|      88|      17
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   72-   87 (27.87/23.08)	IRKRLMHEDALGALED
 1408- 1423 (27.12/ 7.62)	LKDDLMAEENLRALQD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00375 with Med12 domain of Kingdom Fungi
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