<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00322

Description ATP-dependent DNA helicase
SequenceMEVGDVLQELLGVEVELQDVQDQIKVLLDRQEKLYERQSELKSLLEACEDVGSPVRDGASTSGEDWSGTFDWDARADDVKFNIFGIRKYRANQREIINAIMSRRDVLVIMAAGGGKSLCYQLPAILQEGVALVVSPLLSLIQDQVMGLAALGIPAHMLTSTTGKDNEKFIYKALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLIAIDEAHCCSQWGHDFRPDYKNLGILKTQFPSVPVVALTATATWKVQNDLMEMLQIPKCVKFVSTVNRPNLFYMVREKSSVAKVVIDEIAEFIRESYPNNESGIVYCFSRKECEQVAKELRDRGISADYYHADMDVNAREKVHLRWSNGKLQVIIGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECLLYYRAADVPRQSSMVFYENSGLQNLYDIVRYCQSKRQCRRSAFFRHFAEAVQDCNGMCDNCAFSNEIKEIDVSGHAKLVISLLQDVREKDQRLTMLQLVDKIKTMQKELGSNLKKEQLEQLVIQLILDRVLKEEYQHTAYATNAYVTLGPLTKQVLQGKMMIKLEVLSDQKGMNDNIKHTKRGLTTSGLEFKLDELRKELSSIHGGILPHSVLTTQHISTISARKPSSIEELESIIGKLKAGKYGNRILEEVEKYEGSDQPDKNSSRKCQSIDHRASKRPKTKPLVLIETSEDEE
Length708
PositionUnknown
OrganismEucalyptus grandis (Flooded gum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Myrtales> Myrtaceae> Myrtoideae> Eucalypteae> Eucalyptus.
Aromaticity0.07
Grand average of hydropathy-0.380
Instability index42.11
Isoelectric point6.99
Molecular weight80104.04
Publications
PubMed=24919147

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00322
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.83|      60|     211|     283|     350|       1
---------------------------------------------------------------------------
  283-  350 (94.67/92.33)	LFYMVREKSSVAKV..VIDEIAEFIRESYPNnesgivycFSRKECEQ.VAKELRDRGISADYYHADMDVNA
  495-  557 (87.17/65.53)	LLQDVREKDQRLTMlqLVDKIKTMQKELGSN........LKKEQLEQlVIQLILDRVLKEEYQHTAYATNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.58|      41|     118|     121|     166|       2
---------------------------------------------------------------------------
  121-  166 (55.57/61.26)	QLPAIlqEGVALVVSPLLSlIQDQVMGLaaLGIPAHM.LTSTTGKDN
  241-  282 (69.01/53.76)	QFPSV..PVVALTATATWK.VQNDLMEM..LQIPKCVkFVSTVNRPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     185.59|      60|     269|     362|     433|       3
---------------------------------------------------------------------------
  362-  433 (88.51/90.49)	KLQVIIGTVAFGMGINKpdvrfvIHHSLSKsmetyYQESGRAGRDGlPSECL.LYYRAADVPRQSSMVFYENS
  644-  704 (97.08/66.48)	ELESIIGKLKAGKYGNR......ILEEVEK.....YEGSDQPDKNS.SRKCQsIDHRASKRPKTKPLVLIETS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.84|      55|     155|      17|      73|       4
---------------------------------------------------------------------------
   17-   73 (86.08/67.80)	LQDVQDQIKVLLDRQEKLyERQSELKSLLEACEDVG..SPVR.DGASTSGEdWSGTFDWD
  174-  231 (90.76/61.19)	LEKGEGELKILYVTPEKI.SKSKRFMSKLEKCHHAGrlSLIAiDEAHCCSQ.WGHDFRPD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00322 with Med34 domain of Kingdom Viridiplantae
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