<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00252

Description Uncharacterized protein
SequenceMNLLEGPVFIGAFHSLSKVPNDRNCKLQHIYESVQCKEIVFRNIKYVICRALSCISRGGEEGNRVWSEQRKRGVTPEDMGTNTEAIAASSTTLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDVLACSEAVKLLRTMTEEEKTQCCKASLSLLSNKDDPRYIHYERILSSIFMAACNEGVLPLSDCCELLILCTNFTLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSSNSRAFLLPRVAKKFNDMFISFRPLTEMVTIIGRSWLYPIAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTNLTPQRLQCDELLHMIILEAMSEMEKTDARLDDPANQYQWMNITQTVTFSLLHGNASFSRLLKILYESLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSQTDVLPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAIDVFLDGSPEEINTVWHLPYGIISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSIQQTQKLPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLVSVNKNTNLGPAQQDRSRDLLFVLCDILSYRFISYPFPVGSKVNLMLWCYTALGNSQVQMNIALCSALEQVMLRYWMWNSPQEMFYLSNAFLGKQGKLAVIFNVTNPAFCDPQHANIPTEQQYTNSHVSLELLRCLLLSIVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSLHFYQMIGILNDMAFNLHLIPLDRLLTSLVLHPTDDGATEIAMLIIHSLIGSYPDLHNRITALVHIIPSNKIGNTSAAFFNKMSEYYSQFPELSYKEMEAKMRREMQIELGMRPIEQPIVSPELHMPIYYGNIMERILPIVDIILFRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPVFASKDWRFAEMPPAGQALTGACIELLASPHAPLISAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYEHIVSVLDSEALHGDPSVCFGSLENECFLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGVLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRDKLKYISHTQINATVDLPHKLAPGPFSLF
Length1427
PositionTail
OrganismOnchocerca volvulus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.09
Grand average of hydropathy0.021
Instability index44.69
Isoelectric point6.06
Molecular weight162932.06
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00252
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.65|      58|     322|     240|     297|       1
---------------------------------------------------------------------------
  240-  297 (103.35/63.16)	ERMQEVPSTITH..HHRHMLLPVEN...........MLLTLIDRQLNLLP.CIFTITEL.HRVSSNSRAFLLP
  560-  632 (79.30/46.82)	ERTADSDPNIQNvaDHNAVLAAVANayssdmpnfqkLVLTAIDVFLDGSPeEINTVWHLpYGIISYSKKTPLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.76|      37|      40|     636|     674|       2
---------------------------------------------------------------------------
  636-  656 (26.26/10.74)	........................IDSLTFH.ARNHLFQLCLLKLT
  658-  699 (43.20/29.06)	MLSIQQTQKLpSPATIDtlvrlavTTEFEYG.VKQ...VLALLSST
  700-  725 (33.30/13.14)	LVSVNKNTNL.GPAQQD..............rSRDLLFVLC.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      40|    1269|    1288|       3
---------------------------------------------------------------------------
 1269- 1288 (34.66/23.68)	LLTENQLLTNLALGHAYLQH
 1309- 1328 (32.89/22.05)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.50|      21|      40|     906|     930|       4
---------------------------------------------------------------------------
  906-  930 (35.23/31.82)	IHPV......IYSLHFYQMIGILNDmafnLH
  943-  969 (33.27/19.25)	LHPTddgateIAMLIIHSLIGSYPD....LH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.15|      23|      37|    1126|    1162|       6
---------------------------------------------------------------------------
 1116- 1145 (35.57/28.48)	CGQLEDR...dgkyallTPSFISDNHQLS.LPSQ
 1147- 1180 (33.57/30.60)	CQALVDRilqasnyahqPPVFASKDWRFAeMPPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.58|      30|      44|     434|     477|       9
---------------------------------------------------------------------------
  434-  465 (42.74/24.02)	ITQTVTFSllHGNASFSRLLKILYESLSETVY
  864-  893 (46.84/32.44)	QVQEIIYA..QGLAAEEQLLKFFSGERRQTIF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00252 with Med23 domain of Kingdom Metazoa
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