<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00244

Description Uncharacterized protein
SequenceMAFFAESLGETDEQLFVYILMGVLNEDKQQTDIGWVTNLVTRAHAEGMSAIEFGAFLKKRITTSGCNEQQYRAISSMLLRFATASVTPDQRMLSCLEALVKAEVLRWAVFIEVIAEFRQFSREYCIEALATILRNSVPLLKCNYTSEKECLELSGSLMTVLNWCLLALEYSLKNENKRSTQALIHCACAYANSKFVRALLYIHEHIGAESVNYVVEAAVSFAQSYPDCEELKTMTEALQQFDTSPAERIEDNLGGLVKQSHPAILTLVSVFEGFRMTKKVDQMADSFFELAEILEFPFPKMFEDMIRASLLIMLDAKESLGEELVASQAFYYVKLPQIVKHLLILGAPLDDLITALNTICDNKTLLNQVDMKTKTNTFQHLLEQMAAAGVINEGVLKNLLEKRSQYWPELFQMLAQTSTTPVHQPLILRANSAKMAVDKILRQPNNAVINVLLKLASGSGGLFTFDSVCASFCADGNLTYFSAKLAMINGQSERPAEGLDMDDERQRALAFNLSFILLTRIRFIYDDLRPSELVNGTVRGMDNTQSCFFKFASQYGWTAADSCGLSNTYTNEQKAAFVDRVNILKRGQPFWDPRTVNYAELVDFIPVIGEILLDDFRMTKFENYEHLHENIKNVLHAFRDDANFMIVCLVQWMCSQPVTNPRQSLVKSFIRALEYPHQLNHTQQERMVLTSATCRRTLDDLSICDRLRDPRFTWIINCAKRKLPTVPFTLPATNAQSSDAEMLKQAFTYARQQAWGSPNVLQLVDRCNKAGVVENWCMVWLNAMLKLSTNDEMLCASELCLAAGIMSPVPCMLSFARSITEYIFEQNVDFGCVEPKALVSARFLVHCLQLAMHAYWRQQKERQARIVRGECVEKKRSDVDDDGETDQGNPVERSVLVIFEKFVRETRAGHLKSTITFIYHFVVSLATAPPNAATRRIIELLPHDLMLNLARLDPQTFNLDLYLPLMNLCDIANTKSALQFTCLLRKLGGF
Length990
PositionTail
OrganismOnchocerca volvulus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.09
Grand average of hydropathy-0.026
Instability index45.58
Isoelectric point5.77
Molecular weight112109.25
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00244
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.88|      14|      73|     318|     338|       1
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    6-   19 (25.84/ 9.81)	ESLGE..TDEQLFVYI
  318-  333 (21.04/25.04)	ESLGEelVASQAFYYV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     190.72|      60|     347|     349|     422|       2
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  349-  421 (86.48/83.15)	LDDLITALNTIcdnktLLNQVDMkTKTNTFQHLLEQMaaagvinEGVLKNLLEKRSQYWPELFQ.MLAQTSTTP
  601-  661 (104.24/62.78)	LVDFIPVIGEI.....LLDDFRM.TKFENYEHLHENI.......KNVLHAFRDDANFMIVCLVQwMCSQPVTNP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.45|      64|     611|     160|     237|       4
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  160-  237 (92.05/102.51)	VLNWCLLALEYSLKnenkRSTQALIHCA.....CAYANSKfVRALLYIHEHIgaesVNYVVEAAVSFAqsypdCEELKTMTEA
  773-  841 (113.40/80.99)	VENWCMVWLNAMLK....LSTNDEMLCAselclAAGIMSP.VPCMLSFARSI....TEYIFEQNVDFG.....CVEPKALVSA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00244 with Med24 domain of Kingdom Metazoa
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