<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00238

Description Uncharacterized protein
SequenceLRDLKMASCEEEVLRIGRKFERMIQGTKTMDDAMELLNALSALPVDINVLTKTRIGMTINDLRKKTSDEHIAKRAKTLIKEWKVLLANKTSDSKGDTSVTMTRNNSSASVSSTTCNGNSKNLSPSSVSQKSIVSGVANSSTFTPAARKQLLPDEIRNKCATMILDALLSKELPDGTLDPEELAVRTEKKLFEVHRGTSEKYKAALRSRVFNLRDKKNLVLRENILIGAVTPEKFAVMTADEMASDEMKAQREKFTKQAIEEYQMAVQEGTPSDMFKCGKCGKKNCTYTQVQTRSADEPMTTFVFCRECGNRWKFC
Length315
PositionUnknown
OrganismOnchocerca volvulus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.05
Grand average of hydropathy-0.517
Instability index42.98
Isoelectric point9.18
Molecular weight35246.21
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00238
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.86|      16|      18|     103|     119|       1
---------------------------------------------------------------------------
   88-  103 (24.29/16.30)	NKTSDSKGDTSVT.MTR
  104-  120 (22.57/21.38)	NNSSASVSSTTCNgNSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.12|      31|      51|     175|     205|       2
---------------------------------------------------------------------------
  175-  205 (51.31/33.25)	GTLDPEELAVRTEKKL.FEVHRGTSEKY.KAAL
  227-  259 (43.81/27.44)	GAVTPEKFAVMTADEMaSDEMKAQREKFtKQAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.05|      13|      25|     271|     283|       3
---------------------------------------------------------------------------
  271-  283 (27.15/13.68)	PSDMFK.CGKCGKK
  298-  311 (22.90/10.73)	PMTTFVfCRECGNR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00238 with Med26 domain of Kingdom Metazoa

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