<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00236

Description Uncharacterized protein
SequenceMHPHPCLAACLPRKRQEAAAVLISVATGNASSSATTVPAAKKRCMQQQQHPAVASSSGLSAVVPTVESTTVTVVDRLKHQLLQAYDNGDTEQATDVIIKLEKSNLTKELLEMTRIGAVVNDIRKKVAQSAPELSKRCRTLIKCWQKLAEPRPTSSGSSSTNGTPSYASPAVRKGLTPGTPARCPRVISGGNSRLTPARNSHLASLGSSVLTPSGSSGSQSTVTSPTVPNGHTITSYQNSGHEMSMNIAESRTIRKSHTVSADLAIKAVENSLLSGGEIIRNGKRKDENTAISDIGITNGLSAKRPHYSSASVSPTTPHQSLLAAQRADVKSTSELVAQLTENLPGYLAISIPQNQVPARNEHNNNEGQASDANQTLKTPILFTLQPENSKKKEKRGRFKKDKDKKEGRIKDHSVAYGKIIGADNEKASTSAIGNAESELRRNISNNDPSTNKVMVPTRNGKYDWYAMLPSLETLRNREHFRSKPSSNQRKSYIMNVMGREVLALPYIDVGLPDFLEYQYPKPERFYAKENFIYGAPRPN
Length539
PositionUnknown
OrganismOnchocerca volvulus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.04
Grand average of hydropathy-0.614
Instability index43.93
Isoelectric point9.75
Molecular weight58508.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00236
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.21|      40|     152|      47|      91|       1
---------------------------------------------------------------------------
   47-   88 (62.21/43.68)	QQQHPA.....VASSSGLSAVVPTVESTTVTvvDRLKHQLLQAYDNG
  198-  239 (56.29/32.63)	RNSHLAslgssVLTPSGSSGSQSTVTSPTVP.....NGHTITSYQNS
  299-  327 (38.71/21.71)	................GLSAKRPHYSSASVS..PTTPHQSLLAAQRA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.76|      13|      14|     162|     174|       5
---------------------------------------------------------------------------
  162-  174 (23.63/13.86)	GTPSYASPAVRKG
  178-  190 (25.14/15.23)	GTPARCPRVISGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00236 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEPRPTSSGSSSTNGTPSYASPAVRKGLTPGTPARCPRVISGGNSRLTPARNSHLASLGSSVLTPSGSSGSQSTVTSPTVPNGHTITSYQNSGHEMSMNIAESRTIRKS
2) ASTSAIGNAESELRRNISNNDPSTNKVMVP
3) LAISIPQNQVPARNEHNNNEGQASDANQTLKTPILFTLQPENSKKKEKRGRFKKDKDKKEGRIKDHSVA
148
427
347
256
456
415










Molecular Recognition Features






MoRF SequenceStartStop




1) GKYDWYAM
2) KENFIYGAP
460
528
467
536