<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00233

Description Mediator of RNA polymerase II transcription subunit
SequenceMAGQQHPFLSGFPNVQQSAMRTQFGGGQMVSGLIGPQQGNMINPQQFGMGVGVGVGNVGPNAMGMPNSQAQVLAQQQQQQQSIVMQQQMQQMQQQQLQLQQQQQAAMVQQNNQANAQATTPQTPVPPTQQPPPPPQQQQNKEFNTASLCRFGQETVQEIVSRTLELFQTLKVLQPPNGTAQGATMANEKKNKVVEQLKMLKMMYKRLRLIYEKCNENCQLQGMEYTHIESLIPLKEEWDMKSDEKKSSEAYRLACEESKEVMEQVVLKNRHIKEVIDHLRRIISEINTMLNMRRS
Length295
PositionHead
OrganismOoceraea biroi (Clonal raider ant) (Cerapachys biroi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Dorylinae> Ooceraea.
Aromaticity0.04
Grand average of hydropathy-0.724
Instability index65.30
Isoelectric point8.86
Molecular weight33375.87
Publications
PubMed=24508170
PubMed=30249741

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00233
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     217.52|      40|      41|      62|     101|       1
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   11-   51 (49.49/13.28)	..GFPNVQQSAMRTQFGGGQmvsGLIGPQQGNMINPQQFGMGV
   62-  101 (68.80/20.89)	AMGMPNSQAQVLAQQQQQQQ...SIVMQQQMQQMQQQQLQLQQ
  106-  142 (62.20/18.29)	AMVQQNNQAN..AQATTPQT...PVPPTQQPPPPPQQQ.QNKE
  176-  209 (37.04/ 8.37)	....PNGTAQGATMANEKKN...KVVEQLKMLKMMYKRLRL..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00233 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGGQMVSGLIGPQQGNMINPQQFGMGVGVGVGNVGPNAMGMPNSQAQVLAQQQ
2) QQQLQLQQQQQAAMVQQNNQANAQATTPQTPVPPTQQPPPPPQQQQNKEFNTAS
25
94
77
147










Molecular Recognition Features






MoRF SequenceStartStop




NANANA