<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00221

Description Mediator of RNA polymerase II transcription subunit
SequenceMWQKLYNVLTLPMETKVTSKTSSLKALLLRAWRERWTDLKWGINIKTILPRGVSGDVYNLADCILQQALVGLGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCIVSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKAPQSNPLAPHPSELIDKPASILQQMLNSDFLCAMMYLAKYDDKDLYVEVVKKCQEIETLLKTSTQKSVVPIEDSLKKLCNLEIETFCPEKTKMESITHCLQPLFAVQVLLNPSTETTVFVNQLLMVQRLKSYTNARLYCEIIRACFMCLHNVTGTFKESQWGTFTFLKVPLILKELHAASLSADEKFEYSQDILDAFELLLQFTPLLDIMDTTCSCNCVECLLDELQKVNLVTEKQAKQISSRREGATPALQRSELSSTPTSSIPKVITRAEPTLAGILKTLNADYSKIQEPLLKILYQVLTGNSFELMLAVATAEGKLKTFVTKLIKFNECSKQINEPVPDKTAATRAMLFDVSFLMLCSIVQTYGSDVVLEEGGDSFFEQWVRECMPERNKPKSPQRMLHSLDPARVDALLAQINSPDPDFKSSNLKWHVMCQSAMGAVKELLFAWESGVLGAGDVKRALDGLRAAACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLPGDEMPNNLKERSSLMFQIIRKMQYNVHPPTQSKTKVFSMSHSIISRQPILEQLESVWQNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFAVFHLDIENCTIDLINHIIPQYLHNSLQSDELVEPQSSILAKLCVYCIFSTLEYNNSNPYRGNNRKRVRRDLDVDELDALGVPNKLLRLNETSDSVPLFGSQSPQAQGSSNGQMSVVLRDPLMTALNNLFTIFALLAGRDGEVSQQTHFILQFLRLMVQCGKDRTRIVLQGMPQTLVPCLLKALPELFTTDILLRLYDIQSATGRKTTARDLCMLRNINLKPTK
Length1000
PositionTail
OrganismOoceraea biroi (Clonal raider ant) (Cerapachys biroi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Dorylinae> Ooceraea.
Aromaticity0.07
Grand average of hydropathy-0.036
Instability index47.58
Isoelectric point7.00
Molecular weight112720.92
Publications
PubMed=24508170

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00221
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     120.68|      43|      83|     493|     575|       1
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  222-  260 (63.33/25.72)	TQKSVVPIEDSLKKLCNLEIETFCPEKTKMES...ITHCLQP................................................................................................................................................................................................................................................
  497-  500 (-10.21/13.99)	..........................................lfavqvllnpstettvfvnqllmvqrlksytnarlyceiiracfmclhnvtgtfkesqwgtftflkvplilkelhaaslsadekfeysqdildafelllqftplldimdttcscncveclldelqkvnlvtekqakqissrregatpalqrselsstptssipkvitraeptlagilktlnadyskiqepllkilyqvltgnsfelmlavataegklktfvtklikfnecskqinePVPD
  523-  580 (67.55/53.24)	TYGSDVVLEEGGDSFFEQWVRECMPERNKPKSpqrMLHSLDP................................................................................................................................................................................................................................arvdallaqinsPDPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     231.82|      74|      83|      88|     165|       3
---------------------------------------------------------------------------
   48-   77 (25.39/ 7.58)	...................................................ILPR....GVSGDVYNLAD.CILQQALVGLGPNQL
   88-  165 (116.45/70.78)	SQLVSY.AAVLQRISKYDAFhkphCIVSLLEFLES..IQVGITCRGKPEEDLLAA....AVLSIVHWLLQ.CYLHTLTKAPQSNPL
  170-  247 (89.98/46.51)	SELIDKpASILQQMLNSDFL....CAMMYLAKYDDkdLYVEVVKKCQEIETLLKTstqkSVVPIEDSLKKlCNLEIETFCPE....
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.19|      53|     302|     576|     629|       4
---------------------------------------------------------------------------
  576-  629 (91.89/58.86)	SPDPDfKSSNLKWHVMCQSA.MGAVKEL..LFAWESGVLG..AGDVKRALDGLRAAACC
  879-  936 (79.31/46.01)	SPQAQ.GSSNGQMSVVLRDPlMTALNNLftIFALLAGRDGevSQQTHFILQFLRLMVQC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.87|      23|     448|     329|     352|       5
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  329-  352 (34.20/27.34)	LILKELHaASLSADEKFEYSQDIL
  794-  816 (40.68/27.84)	IIPQYLH.NSLQSDELVEPQSSIL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.74|      43|     381|     267|     311|       9
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  267-  311 (71.22/54.91)	LLNPSTETTVFVNQL...LMVQRLKsyTNARLYCEIIRACFMCLHNVT
  650-  695 (73.53/49.67)	LLKPMNMVQHFLTPLpgdEMPNNLK..ERSSLMFQIIRKMQYNVHPPT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00221 with Med24 domain of Kingdom Metazoa
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