<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00194

Description Uncharacterized protein
SequenceMPIFGDTFSANDAFNDTIEDDINAKAPSIDYYAILALPRDATTAEIRNRYLMLSREFHPDRLRHRLQRTDITPERLDALEDFATFTFPTIDRAYKILCDPTKRFAYDMYGEEGVLALENDTTNDLKSREALNTYLRSKEKLDQYIQQIIQAMNQAKLRASFISLSDVVMHVDASDFYSHPFQSIRKFGQSEYQSITRTEMTMRQQFVIPINNSTRWTFGAYLMDRENLAMGGLTSQIAYTGSDVTLPSVTFSTQMGWKPKCALQCSQPISPYTAGTLSWEYDETGIQIGGSVQHALTAQTHGQMMWGTREGLTLGVANDTTNYKTSFRIGVGSRVSMLMTVQDENGQYQSVPIVRKMAVPQITCAGKYNISPKTNIRGSFSGDLLLRQISVSLGSAFNVAQKAKIAIDVLLAYTGVTFQFGCKRGNVRFVIPIFLAPFSNTTALGAFIAATSPHFVSAIVAQILKPRLQHRQRVIRRQFEDNRNRQIEIQKDVASKQQILMQRTASEKRQQEIARSVAARDSSNQTPMNSGLVILLARYGCCVEDEGVKHDQSDASIENECLSFSDQESVENSEVLYQESENFERGTVSQWTDVTIPIQFFVQNGRLELPAQSKAHLLGFYNPCGTAKQDALVPSPQLYIRYVYNDLVYEVTFEDHEQVQLPSKFARVMGSAKLPIDNPSITGFISMPGVGDYVECALQEHRSIVTNLLESINTASLPPSTITNIRLRSVQEQVHRLLESDRRLATAVKTLWTHQITQKTLFQLQNEIKAKEERVIEYATQLRNAQVAIQNVFEKHQYVLQQVRKPKQQQVFLDPQLLVAYAHRIAGTTSAPKHWQPGLPMSGFAPPAPQEQIMRAGVLSRGVIAETVTRDGFKPTRIDVLTDSDLSGANDLKTPIGLGATDAEIRNQMPPGWKPGDPVDLPLDALLHYMGRSFFQEHGITLPESWRNGDAVPPEAMDLLRKKFNLPEKRKSDEMNVNAEMSQKKRKLETDDENSEESSDSESSSDQDTPQGISLSFSSSSDEDE
Length1025
PositionMiddle
OrganismAlbugo candida
KingdomOomycetes
LineageEukaryota> Sar> Stramenopiles> Oomycota> Albuginales> Albuginaceae> Albugo.
Aromaticity0.08
Grand average of hydropathy-0.423
Instability index47.97
Isoelectric point5.81
Molecular weight115148.68
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00194
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     177.74|      57|     653|     139|     291|       1
---------------------------------------------------------------------------
   29-   92 (81.19/17.49)	IDYYaILALPRDATTAEIRNRYLMLSrefhpDRLRHrLQRTDITPERLDALEDFATFTFPTIDR
  141-  197 (96.55/200.28)	LDQY.IQQIIQAMNQAKLRASFISLS.....DVVMH.VDASDFYSHPFQSIRKFGQSEYQSITR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.52|      19|      40|     280|     299|       2
---------------------------------------------------------------------------
  280-  299 (30.18/25.92)	EYdETGIQIG.GS.VQHALTAQ
  322-  342 (26.33/16.54)	NY.KTSFRIGvGSrVSMLMTVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     184.37|      46|     653|     214|     259|       5
---------------------------------------------------------------------------
  214-  259 (86.36/50.52)	TRWTFGA....YLMDRENLAMGGLTSQIAYTGSDVTLPSVTFSTQM..GWKP
  579-  605 (36.15/17.27)	..............ESENFER.GTVSQ....WTDVTIP.IQFFVQN..G...
  869-  915 (61.87/34.30)	TRDGFKPtridVLTDSDLSGANDLKTPIGLGATDAEIRN.....QMppGWKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.88|      22|      23|     472|     494|       6
---------------------------------------------------------------------------
  472-  494 (32.94/23.83)	QRVIRrQFEDNRNRQIEIQKDVA
  497-  518 (35.94/21.28)	QQILM.QRTASEKRQQEIARSVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.95|      15|     196|     108|     122|       7
---------------------------------------------------------------------------
  108-  122 (28.50/19.74)	MYG.EEGV.LALENDTT
  305-  321 (21.45/13.09)	MWGtREGLtLGVANDTT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.25|      41|      41|     739|     779|       8
---------------------------------------------------------------------------
  710-  738 (45.31/28.86)	ES...INTA..SLP.PSTITNIRLRSVQ.......EQV.......HRLL
  739-  779 (67.45/46.58)	ESDRRLATAVKTLW.THQITQKTLFQLQNEIKAKEERV.......IEYA
  780-  822 (44.48/28.19)	TQLRNAQVAIQNVFeKHQ......YVLQQVRKPKQQQVfldpqllVAYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.63|      22|      48|     373|     397|       9
---------------------------------------------------------------------------
  373-  397 (27.98/31.99)	KTNIRgsFSGDLLLRQIS..VSLGsAF
  402-  420 (29.56/19.65)	KAKI....AIDVLLAYTG..VTF..QF
  424-  447 (33.09/22.98)	RGNVR..FVIPIFLAPFSntTALG.AF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00194 with Med4 domain of Kingdom Oomycetes


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DLKTPIGLGATDAEIRNQMPPGWKPGDPVDL
2) ITLPESWRNGDAVPPEAMDLLRKKFNLPEKRKSDEMNVNAEMSQKKRKLETDDENSEESSDSESSSDQDTPQGISLSFSSSSDEDE
891
940
921
1025










Molecular Recognition Features






MoRF SequenceStartStop




1) DLLRKKFNL
2) MSQKKRKLETD
3) SSSDQDTPQGISLSFSSSSDEDE
958
981
1003
966
991
1025