<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00169

Description Uncharacterized protein
SequenceMQRYHAGNCTSAVNNNSTIGGIRDTSHIDTPAVPSNFSLNPRRPSQITLYKLRCDKEPLNSRLGPPDFHPQTPNCPEETLTREYVQAGYRETVEGLEEAREIPLSQVQAFTRPVIFKCKEAIRKCHRAIIESRTKKRKAGQVYEVPLSGNLLIKSGIFPELRPCGEDFRKKWIEGLSQPHKRLRSLADHVPHGYRRKSLFEVLIRNNVPLLRATWFIKVTYLNQVRAASSNSSSSFNGKTQFSRSEQWTKDVIEYLQYLLDEFMARNISHSTLHMRERSSQIYTGSVQPQGDSFSAAVDGEEPSLYTKWWYVVRIIHWHHAEGLLVPSLIIDWVLNQLQQKESLGVLQLLLPIIYGVIETVVLSQNYVRILVKIAIRFIQEPSPGGSDLVDNSRRAYTTSAIVEMLRYLVLVVPDTFVALDCFPLPVCVVSHVVNDGSFLSKKVEDARKVKGGRIGAGDKNQADSLSFHSVVSSVKKRAETLSTAARPNHSGYNVAKVLQMLDQALVHGDIGGSYKLLFENLWDGACAENWLTKVSPCLHTSLKHIRSVTSSLICSIFFVFEWATCEFRDFRTAPPHGLKFTGRKDLSQILIAIRILKLRVSKMPNMYTSKQRSRNIPDIFESPGPLHDIILCWIDQHEVHNKEGFKRVQLQIRELIVSKFFNPLAYVRQLIISGIMDENGPMVDLEKRKRHYKLLKELPAAYIRDALEEAQIAEPSIILDAINIYSNERKMVLRGLLGNRKSNPSANGSNKRQAHQKSYRSGSCSPSSVERWYFQEASNVSTANLDTDTKLEELKASISALLQFPVPSSSIDSGINESQGNLKRSGGGYSGADVSEETSGCEECKRAKRQKISEERSSLLQSYPADEEEKWWVKKGVKYIENSRVEPPPKPVKQSSSRGRQKSVRKTQSLAQLADARIEGSQGASTSHVCESRIGCPHHRAGYDEISKPVDGTRKPPCADIVLIRKLLKQMQFIKKRTIAVWLISVVKQLIEESEAFTAKVGQYGRQLPPVDDRSSKQWRLGEDELSVILYIMDVCNELVAAIRFLFWLFPKVPSYPPSTLHGRNILTLPKIAENHACEVGEAFLLSCIRRYENIIIASDLIPETLSATMRRTAGVMASSGRLSVSPALVYARHLLRKYGSISSIVEWEKAFYPTCDKRLSSELESAKSLDGDFGFPLGVPNGVGDPDDYFRQKIGGVRIAKQIVMGLLDCMRQTGGAAQEGDPSLVSSAIAAIVHNIGQVFAKIPDLTAGSNHLHASPPYGSLHFTQRILRIHITCLCVLKEALGERQSRVFEVALATEASSALMQAFSASSPNEALNHSNKAVLGRAARISAAVSALVIGAILQGVASLERMVTLFRLKEGLDLVQFARNLKSNVNGNARSVGVLKVDNLIEVSVNWFRVLVGNCRTVSDGLIVDLLGEASIVALFRMQRMLPLNLVFPPAYSIFSFVIWRPVIDGSFGAREDFHHLYQLLGVAANDAIKHLPFREICLRDTYGLYDLIAADNLDSEFVSMLEFNGSDMSLKAAALVPLRSRLFLDALIDCKMPQPVVKLDDKNSVSKQVELKKQCGENVKKLMGKLVHVLNTLQPAKFHWQWVELRLLLNEQSVNEKMENDTSLAEAIRSLSPIPDKSTGSENESNFIQIVLTRLLIRPDAAPLFSEVVHLLGKSLEDSMLSQAKWLLRGAEVLYGKKSIRQKVVNIAAGIKEVCLKPQYWKPWGWCRSDTNRVTDKGDKWKSEGSALEEGEVVDEGAADFNQPGKESGLSDIEGLTVSQQHVTERALVELILPCLDQGPDDLRYNFASEMIKQISNIEQQINAVTRGVGKQGVTPSTVIGSPASKGGSRKSGKSGSPGISRQSTGAADNTVPPSPVALRASMTLRLQFLIRLLPIICLDREPLGRNIRYTLAPVILRLLGSRVVHEDAGHFISPIFTSSKRDVNPLKEASAELLSGENIFDSLLLVLHALLSCYQPSWLKSKSESKPTESSKDYAAFDREVAESLQNELDRMELPETIRWRIQTAMPILLPPVKCSINCQPPSVPPTVLTRLMPITQVTTVNPNHNNSNPSQRSPILPGHIVKNKQHALQLELDSSEIIDQWTLLEEGTGSGGPPLATSAGISGSGQSNLKASNLLKGAIRVRRKDLTYVGAVDEDS
Length2152
PositionKinase
OrganismErythranthe guttata (Yellow monkey flower) (Mimulus guttatus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Phrymaceae> Erythranthe.
Aromaticity0.07
Grand average of hydropathy-0.228
Instability index48.96
Isoelectric point8.99
Molecular weight239229.78
Publications
PubMed=24225854

Function

Annotated function 
ECO:0000256	RuleBase:RU364129
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions











Repeat regions





Repeats
>MDP00169
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     456.57|     120|     975|      70|     209|       1
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   70-  195 (199.47/135.52)	PQTPNCPEETLtreyvQAGYRET..VEGLEEAREIPLSQV.QAFTRPVI...FKCKEAIRKCHRAIIE..SRTKKRKAGQVYEVPLSGNLL.....IKS........G.IFPE..LRPCGE.DFRKKWiEGLSQP..HKRLRSLADHVPHGYR
  902- 1021 (128.03/73.61)	................QKSVRKTqsLAQLADAR.IEGSQ..GASTSHVCesrIGCPHH.RAGYDEISK..PVDGTRKP.PCADIVLIRKLLkqmqfIKKrtiavwliS.VVKQ..LIEESE.AFTAK....VGQY..GRQLPPVDDRSSKQWR
 1052- 1163 (129.07/84.95)	PKVPSYPPSTL........HGRN..ILTLPKIAENHACEVgEAFLLSCI...RR.YENIIIASDLIPEtlSATMRRTAGVMAS...SGRLS.....VSP........AlVYARhlLRKYGSiSSIVEW.EKAFYPtcDKRLSS..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     297.51|      98|     820|    1225|    1333|       7
---------------------------------------------------------------------------
 1225- 1333 (139.86/105.61)	PSLVSSAIAAIVhNIGQVFAKIPDlTAGSNHLHASP..PYGSLHFTQRILRIHITCLCVLKE.ALGERQSRVFEVALATEAssalmqAFSASSPNEaLNHSNkaVLGRAARI
 2037- 2137 (157.65/89.80)	PSVPPTVLTRLM.PITQVTTVNPN.HNNSNPSQRSPilPGHIVKNKQHALQLELDSSEIIDQwTLLEEGTGSGGPPLATSA......GISGSGQSN.LKASN..LLKGAIRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.49|      56|     278|    1618|    1675|       9
---------------------------------------------------------------------------
 1618- 1675 (90.07/53.53)	LAEAIR.SLSPIPDKSTGS....ENESNFIQIVLTRllIRPDAAPLFSEVVHLL.GKSLEDSML
 1898- 1959 (80.43/42.72)	LGRNIRyTLAPVILRLLGSrvvhEDAGHFISPIFTS..SKRDVNPLKEASAELLsGENIFDSLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00169 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DSGINESQGNLKRSGGGYSGADVSEETSGCEECKRAK
2) GVTPSTVIGSPASKGGSRKSGKSGSPGISRQSTGAADNTVP
3) SRVEPPPKPVKQSSSRGRQKSVRKTQSLAQLADARI
4) YHAGNCTSAVNNNSTIGGIRDTSHIDTPAVPSNFSLN
813
1827
884
4
849
1867
919
40










Molecular Recognition Features






MoRF SequenceStartStop




NANANA