<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00136

Description Uncharacterized protein
SequenceMNCSNKLHKVNWSDHAKAHNNFSSQDKFLSANFLFSLPTQKPQIGEAMGTRLTIFPIIFIYSYYIIRMLNMFMLIESILCIIIMVTILQYLCFLFLKLFFSAWQLLSKLQLSSRNYNKLGKTLPLSKDVNAFTSQSSRRTTQQCLPGSKSTAAVCNQTYQSFSNGDVQTSKPNKSLDSSFPPNTFEAKEARQVMFGQKGSHSSTNDTSQRQTINSTAGKSAVHVSARNGPTVLDGIDEDDIMENIDVDRIVSDHYQSTPQPSISKLPPITPHTKKDNFLNEEINLPSELCVMCNHNYKLGLCPEASNHLQAMKDSLIAISNDLIDNVDEMSPEQVETLRQERQQLKKQVQQLEKYLNTTSVNEERNMSQFSASTTAPRAFQSDTPSTMPFRIDPRRLDTQFQANNEPYGFDRWGSSSTSFSADGFGTSTAPFEREPYVPKYIDINYIDGSNDKKWSSREFSWTKELEVNNKKVFGNHSFRPNQREVINATMSGHDVFVLMPTGGGKSLTYQLPALVCPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMEWSEQQEIFRELSSDYCKYKLLYVTPEKVAKSDVLLRQLENLHARESLARFVIDEAHCVSQWGHDFRPDYQGLGILKQKFPTIPVLALTATATISVKEDVVQALGLVNCIVFRQSFNRPNLRYSVVPKTRKCVEDIDKFIRENHFDECGIIYCLSRMDCEKVAEKLQEYGHKSAFYHGSMESTQRSMVQRQWSKDEVNIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCVLYYSYSDYIRVKHMISQGAAEQTPFGSGYSRTNTGQSGRLLETNTENLLRMVSYSENDVDCRRLLQLVHFGEKFDSLNCQKTCDNCSKNQSCVEKDVTGTARQLVELVKTTGQQFSAAHLLEVYRGSLSQFVKKHRHENLSLHGAGKHLAKGEASRVLRHLVIEDILVEDVKKSDLYGSVSSIVKVNGSKAYNLFSGAQTIKLRFPSAPKASKPGRTEATPAKGSMISEKQSPIQIDTPAQPPSEVDLNLSAKLYNSLRMLRIVLLKEAGDGFSAYHIFGNATLQLISMKIPRNRDELLEINGIGKAKITKYGDRVLETIEATIRDYYNKDKSSSSSNDSSESKKRRNVANNVSNEDDFTESTGRSKRRLTKNRNKSPEVIDCSLIDGLEDIDFDDNLFDVSVGEVDQGGGGRALPSWSTNGK
Length1222
PositionUnknown
OrganismErythranthe guttata (Yellow monkey flower) (Mimulus guttatus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Phrymaceae> Erythranthe.
Aromaticity0.08
Grand average of hydropathy-0.470
Instability index44.11
Isoelectric point8.20
Molecular weight137346.81
Publications
PubMed=24225854

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00136
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.32|      33|      62|    1093|    1125|       1
---------------------------------------------------------------------------
 1093- 1125 (53.84/38.94)	NRDELLEINGIGKAKITKYGDRVLETIEATIRD
 1154- 1186 (56.47/41.23)	NEDDFTESTGRSKRRLTKNRNKSPEVIDCSLID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.43|      49|     204|     609|     694|       2
---------------------------------------------------------------------------
  646-  694 (83.28/106.50)	ISVKEDVVQALGLVNCIVFRQSFNRPNLRYSV..VPKTRKCVE.DIDKFIRE
  851-  902 (78.15/35.29)	VSYSENDVDCRRLLQLVHFGEKFDSLNCQKTCdnCSKNQSCVEkDVTGTARQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.57|      13|     650|     381|     393|       3
---------------------------------------------------------------------------
  381-  393 (25.57/15.48)	QSDTPSTMPFRID
 1034- 1046 (25.00/14.97)	QIDTPAQPPSEVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.90|      15|      20|     121|     135|       5
---------------------------------------------------------------------------
  121-  135 (25.48/13.48)	KTLPLSKDVNAFTSQ
  143-  157 (26.42/14.23)	QCLPGSKSTAAVCNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00136 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKEARQVMFGQKGSHSSTNDTSQRQTINSTAGKSAVHVSARNGPTVLDGIDEDD
2) EERNMSQFSASTTAPRAFQSDTPSTMPFRIDPRRLD
3) ENIDVDRIVSDHYQSTPQPSISKLPPITPHTKKDNFLN
4) PSAPKASKPGRTEATPAKGSMISEKQSPIQIDTPAQP
5) YNKDKSSSSSNDSSESKKRRNVANNVSNEDDFTESTGRSKRRLTKNR
187
363
243
1005
1127
240
398
280
1041
1173










Molecular Recognition Features






MoRF SequenceStartStop




1) RALPSW
1212
1217