<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00133

Description Uncharacterized protein
SequenceMAVAWKRRASSIIFAFVLIGSLFAFSIAAEEEEAPKVGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFTDSERLIGEAAKNQFAVNPERTVFDVKRLIGRKFEDKEVQKDMKLVPYKIVNRDGKPYIQVKIRDGETKVFSPEEVSAMILTKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDHRALGKLRREAERAKRSLSSQHQVRVEIESLFDGVDLSEPLTRARFEEMNNDLFRKTMGPVKKAMEDAGLEKRQIDEIVLVGGSTRIPKIQQLLKDFFDGKEPNKGVNPDEAVAYGAAVQGGIISGEGGDETKDLLLLDVAPLTLGIETVGGVMTKLIPRNTVIPTSKSQVFTTYQDQQTTVTIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGIPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKGRLSQEEIERMVKEAEEFAEEDKKVKERIDARNSLETYVYNMRNQINDKDKLADKLETDEKEKIETATKEALEWLDENQSAEKEDYEEKLKEVEAVCNPIITAVYQRSGGAPEGKTDEDEDDHDEL
Length667
PositionUnknown
OrganismErythranthe guttata (Yellow monkey flower) (Mimulus guttatus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Phrymaceae> Erythranthe.
Aromaticity0.06
Grand average of hydropathy-0.470
Instability index30.80
Isoelectric point5.07
Molecular weight74083.04
Publications
PubMed=24225854

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00133
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      31|     234|     244|       1
---------------------------------------------------------------------------
  234-  244 (20.46/10.52)	LGGGTFDVSIL
  262-  272 (21.85/11.68)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     375.81|      93|     193|     132|     233|       2
---------------------------------------------------------------------------
  132-  226 (141.58/85.52)	DG....KPYIQVKIRDGETKVFSPEevSAMILTKMKETAEAYLGKKIKDAVVTVPAYFNDAQ.RQATKDAGTIAGLNVVRIINEPTAAA...IAYG.......LDKKGGE
  323-  420 (120.32/66.52)	DGvdlsEPLTRARFEEMNNDLFR....KTMGPVK.KAMEDAGLEKRQIDEIVLVGGSTRIPKiQQLLKD..FFDGKEPNKGVN.PD.EA...VAYGaavqggiISGEGGD
  434-  518 (113.91/70.39)	T........LGIETVGGVMTKLIPR..NTVIPTSKSQVFTTY.....QDQQTTVTIQVFEGE.RSLTKDCRLLGKFDLTGIAPAPRGIPqieVTFE.......VDANG..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.97|      17|      21|      69|      86|       3
---------------------------------------------------------------------------
   69-   86 (28.40/23.04)	NR..ITPSWVGFtDSERLIG
   91-  109 (23.56/13.68)	NQfaVNPERTVF.DVKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.85|      48|      55|     547|     601|       4
---------------------------------------------------------------------------
  547-  601 (72.91/61.31)	EEIERMVKEAEEFAEE.........DKKVKERIDARNSLETYVYnmrnqinDKDKLADKLETDE
  603-  659 (72.94/46.70)	EKIETATKEALEWLDEnqsaekedyEEKLKEVEAVCNPIITAVY.......QRSGGAPEGKTDE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00133 with Med37 domain of Kingdom Viridiplantae
Unable to open file!