<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00125

Description Uncharacterized protein
SequenceMGDGRAGNSSSKPEWLEQYDVIGKIGEGTYGLVFLAKIKANRSKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKVNQAINPYTVKSILWQLLNGLNYLHSNWIVHRDLKPSNILVMGDGEEHGVVKIADFGLARIYQAPLKPLHENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKGTPNPFQLDQLDKIFKVLGHPTPEKWPMLVHLPHWQTDLQHIQGHTYNNAGLYNVIHLSPKNAAYDLLSKMLEYDPKKRLTAAEALDHEYFRHEPLAGCNSLVPPQPGDKVVNYPTRPVDTATDIEGTISLQPSQPISSGNNMPGGMAGQHVMQNRSMPRPMAMVGMQRTQPPPGIPAYNLASQAAMGGGVNPGGVPMQRGVAPQPQQQQQGRRKDPGMGMTGYPPQQRSRRF
Length469
PositionKinase
OrganismErythranthe guttata (Yellow monkey flower) (Mimulus guttatus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Phrymaceae> Erythranthe.
Aromaticity0.07
Grand average of hydropathy-0.422
Instability index41.32
Isoelectric point8.99
Molecular weight52256.36
Publications
PubMed=24225854

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00125
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     184.08|      41|      42|     368|     408|       1
---------------------------------------------------------------------------
  330-  358 (39.31/15.84)	.............EP...LAGCNSLVP.PQ.PGDKVVNYPTRPVDTA
  361-  399 (70.29/33.84)	IEG..TI.SLQPSQP...ISSGNNMPG.GM.AGQHVMQNRSMPRPMA
  400-  431 (32.95/12.14)	MVGMQRT.QPPPGIPaynLASQAAMGG.GVnPGG.............
  432-  466 (41.53/17.12)	.VPMQRGvAPQPQQQ...QQGRRKDPGmGM.TG.YPPQQRS......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     162.64|      42|      42|     142|     183|       2
---------------------------------------------------------------------------
   99-  122 (28.26/14.41)	.................DYAEHDLYEIIRHHRDKVNQA...INP
  142-  183 (72.59/47.57)	NWIVHRDLKPSNILVMGDGEEHGVVKIADFGLARIYQA..PLKP
  187-  228 (61.80/39.50)	NGVVVTIWYRAPELLLGAKHYTSAVDMWAVGC..IFAEllTLKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00125 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LAGCNSLVPPQPGDKVVNYPTRPVDTATDIEGTISLQPSQPISSGNNMPGGMAGQHVMQNRSMPRPMAMVGMQRTQPPPGIPAYNLASQAAMGGGVNPGGVPMQRGVAPQPQQQQQGRRKDPGMGMTGYPPQQRSRRF
332
469










Molecular Recognition Features






MoRF SequenceStartStop




1) KSIAIKKFK
2) YPPQQRS
44
460
52
466