<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00066

Description Uncharacterized protein
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
Length576
PositionKinase
OrganismAncylostoma ceylanicum
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Ancylostomatoidea> Ancylostomatidae> Ancylostomatinae> Ancylostoma.
Aromaticity0.09
Grand average of hydropathy-0.658
Instability index62.28
Isoelectric point8.69
Molecular weight66601.26
Publications
PubMed=25730766

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00066
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     249.27|      31|      31|     431|     461|       1
---------------------------------------------------------------------------
  394-  423 (35.31/ 9.96)	QTMNQQldsEPVNKRLRMGG.....qQMN...ANSQ....PM
  431-  461 (66.73/24.77)	QPMQTQ...HMISQSMDMGG......MMNQ..PQQQYQQPPI
  465-  493 (54.04/18.79)	QPMPTS...MPVSGQQQMG.......MM.Q..GQQQFQHQNM
  494-  514 (34.13/ 9.41)	GMMQGQ...PMM..............MRQQ..MPPTYQQH..
  515-  535 (28.72/ 6.86)	.P...Q...GMMQQS..GGG....vdMMSS..M......PPG
  539-  568 (30.32/ 7.61)	QQMGIQ..........NMGGnpppysMMQQqgPQQPQQQP..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     130.10|      32|      32|     296|     327|       2
---------------------------------------------------------------------------
  240-  268 (31.12/15.10)	.....FCKEEDIKAQ..SPyHYDQLKRIFTvMGY...PQ
  273-  297 (23.17/ 9.51)	TDFKKMPDYHKLQTDikSS.Q.............tafPN
  298-  327 (49.66/28.14)	CSMTRYMEKHKIESD..SP.QFKLLVKLLT.MDP.....
  331-  346 (26.15/11.60)	ISCKDAMEE.........P.YFK........MDP.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.71|      31|      37|     122|     157|       3
---------------------------------------------------------------------------
  122-  157 (50.25/42.74)	MPVMVPKGMVKSILYQILD.GIHYLHSNwvlhrDLKP
  160-  191 (50.46/30.11)	ILVMGDAPGVHRGRVKIADmGFARIFYN.....PLKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00066 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SLPDADIKKSLAMNIVDDQNQQATNPQVNQTMNQQLDSEPVNKRLRMGGQQMNANSQPMFPSGEFHQPMQTQHMISQSMDMGGMMNQPQQQYQQPPIFASQPMPTSMPVSGQQQMGMMQGQQQFQHQNMGMMQGQPMMMRQQMPPTYQQHPQGMMQQSGGGVDMMSSMPPGMHNQQMGIQNMGGNPPPYSMMQQQGPQQPQQQPQQQWNHYQ
365
576










Molecular Recognition Features






MoRF SequenceStartStop




NANANA