<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00064

Description Uncharacterized protein
SequenceMYPSGSGTFTGGPGAVRKGADISLEAVNEWKIQEIGYDGVEKYIKPPSFSDNVGKLARQVDWQKLIGSDAVYDNPNAIKSETEEEEEPGSTTYCAFSFPFGQVQICRTSTFMCWLQTVETKPVEIEERVIPEAGPWHNVAKYLHESLQQFNVLLDNLAIMRATDYMKPLTILDPIHAESAPMQAENAAASKATQWVWKRKALLEAMSVLELAQRLRNVEVEDEAHQQKSQFFMELTKMREYWRVRKTGDHIYGDLGYRIFGSKYNPRELFDITRRSLTPGTSFDASTSVLQVSVPRDLTRRSTLAVSIVKDDYTNRDLFASLDDHQFEYMKVDSSKIESIHWASALKWAQETLICKDIFNTLCSDAVQMRNRLSTVRDGVLLVSLYNDYLLRVELKYHPFREGELIEEGCPYLNRSLREMMVSQECTRWVRPQTFVSLPLTNLSEALDARGPRAFTAREIESRAHKPQFLLEKLIVVASHYSLVKMARETLEEFMSSTRDPQVHWRWLRCSPISSQFMVILTNRNFDYVVGKVTYYIRVTADSVCLISKDGHSMDCYRDPNQLMYALKYMACTFSVTSISTLGKVMWFYQLLHANMNATDEHGRPAPTLYMLNPDATMEVFVRFGIDQNPLIQVRKFQGATKYEDQVHVPFTTLNYDRLRGSTLCRKMDNLFAAFRDIDE
Length680
PositionHead
OrganismAncylostoma ceylanicum
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Ancylostomatoidea> Ancylostomatidae> Ancylostomatinae> Ancylostoma.
Aromaticity0.10
Grand average of hydropathy-0.350
Instability index44.01
Isoelectric point6.08
Molecular weight78210.32
Publications
PubMed=25730766

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP00064
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.80|      15|     162|     328|     348|       2
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  328-  348 (20.50/28.28)	EYMkvDSSKIESIHWasalKW
  493-  507 (32.30/21.31)	EFM..SSTRDPQVHW....RW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.82|      42|     188|      64|     110|       5
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   64-  110 (59.13/55.55)	KLIGSDavYdNPNAIKSETEEEEEPGsTTYCAfSFPFGQVQICRTST
  258-  299 (73.69/46.51)	RIFGSK..Y.NPRELFDITRRSLTPG.TSFDA.STSVLQVSVPRDLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.55|      21|     283|     229|     257|       8
---------------------------------------------------------------------------
  229-  257 (29.70/42.95)	SQFFMELTKmREYwrvrktgDHIYGDLGY
  515-  535 (38.85/26.51)	SQFMVILTN.RNF.......DYVVGKVTY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP00064 with Med17 domain of Kingdom Metazoa

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