PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_5282	AGGL_ABRPR	--NA--	"Abrus precatorius"	Fabaceae	--NA--	Signaling-peptide	"3D-structure; Direct protein sequencing; Glycoprotein; Hydrolase; Lectin; Plant defense; Protein synthesis inhibitor; Pyrrolidone carboxylic acid; Repeat; Signal; Toxin | Agglutinin-1 precursor (Agglutinin I) [Contains: Agglutinin-1 chain A,(EC 3.2.2.22) (AAG-A); Agglutinin-1 chain B (AAG-B)]."	--NA--	EALRQGIKFLRSGASDDEEIARTLIVIIQMVAEAARFRYVSKLVVISLSNGTLTVQKNDYRMRQGWRTGNDTSPFVTSIAGFFKLCMEAHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQNTNNCLTCEEHKQGATIVMMGCSNAWASQRLIYGIPVLRDPSTVEKPNQYVTVELSYSDTVSIQLGIDLTNAYVVAYRAGLSHPSVSALALMLFVCNPLNATQSPLLIRSVVEQSKICSSHYEPTVRIGGMKFETTKNKLHGNAYYQAQFQDPIKFTTGSATPASYNQFIDALRERLTGGRAAFQPDPSMLSLENTWEPLSRAVQHTVQDTFPQNVTLINVRQERVVVSSRDGLCVDVSDNAYNNGNPIILWKCKDQLEVNQLWTLKSDKTIRSKGKCLTSESFFFRNAPASASTYLFTGTQQYSLPFDGNYDDLEKWAHQSRQRISLGLTYGYAPGNYVMIYDCSSAVAEATYWDIWDNGTIINPKSGLVLSAESSSMGWVFKSDGTIYNLYDDMVMDVKSSDPSLKQIILWPYTGNANQMWATLF	547	"Experimental evidence at protein level"	61248.33	61209.34	5.9	--NA--	"FUNCTION:The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA (By similarity). Less toxic than abrin-a.FUNCTION:The B chain is a galactose-specific lectin that facilitates the binding to the cell membrane that precedes endocytosis (By similarity).CATALYTIC ACTIVITY:Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.SUBUNIT:Heterotetramer of two A and two B chains.DOMAIN:The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).MISCELLANEOUS:Induces cytokine production and proliferation of splenocytes and thymocytes in mice.SIMILARITY:In the N-terminal section; belongs to the ribosome- inactivating protein family. Type 2 RIP subfamily.SIMILARITY:Contains 2 ricin B-type lectin domains."