PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_4869	ABRC_ABRPR	--NA--	"Abrus precatorius"	Fabaceae	--NA--	Signaling-peptide	"Glycoprotein; Hydrolase; Lectin; Plant defense; Protein synthesis inhibitor; Pyrrolidone carboxylic acid; Repeat; Signal; Toxin | Abrin-c precursor [Contains: Abrin-c A chain (EC 3.2.2.22) (rRNA N-,glycosidase); Linker peptide; Abrin-c B chain]."	--NA--	CMQAQGSNVWLADCDNNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSERWAHQTREEISLGLQALTHAISFLRSGASNDEEKARTLIVIIQMASEAAGIDVTNAYVVAYRAGSQSYFLRDAPASASTYLFPGTQRYSLRFDGSYGDLHGKPNQIWLTLFKICSSRYEPTVRIGGRDGMCVDVYDDGYHNGNRIIAWKCKDRLEENQLWTLKSDKTIRSNGKCLTTEGYAPGNYVMIYDCTSAVAEATYWEIWDNGTIINMDKTLKLLILCLAWTCSFSALRCAARTYPPVATNQDQVIKFTTEGATSQSPIVLMACSNGWASQRWLFKNDGSIYNLHDDMVMDVKRSDPSLKEIILHPYPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLRYRYISNRVGVSIRTGTAFQPDPAMLSLENNWDNLSGGVQQSVQDTFPNNVILSSINRQPVVVDSLSHPTVAVLALMLFVCNPPNANQSPLLIRSIVEESYKQFIEALRQRLTGGLIHDIPVLPDPTTVEERNRYITVELSNSERESIEV	562	"Experimental evidence at protein level"	62817.82	62778.12	5.93	--NA--	"FUNCTION:The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.Abrin-a is more toxic than ricin.FUNCTION:The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.CATALYTIC ACTIVITY:Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.SUBUNIT:Disulfide-linked dimer of A and B chains.DOMAIN:The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).SIMILARITY:In the N-terminal section; belongs to the ribosome- inactivating protein family. Type 2 RIP subfamily.SIMILARITY:Contains 2 ricin B-type lectin domains."