PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_4688	CYSEP_RICCO	--NA--	"Ricinus communis"	Euphorbiaceae	--NA--	Signaling-peptide	"3D-structure; Direct protein sequencing; Hydrolase; Protease; Signal; Thiol protease | Vignain precursor (EC 3.4.22.-) (Cysteine endopeptidase).Note=The pro-endopeptidase accumulates in the ricinosomes."	--NA--	AVANQPVSVAIDAGGSDFQFYSEGVFTGSCGTELDHGVAIVGYGTTIDGTGIKSSPKDELIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPENDENALLKKVKHHRMFRGGPRGNGTFMYEKVDTVPASVDWRKKGAVTSVKDQGQCGSCKYWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPIKKSSNNPSLHEKQKRFNVFKHNAMHVHNANKMDKPYKLKLNKFADMTNHEFRNTYSGSMQKFILLALSLALVLAITESFDFHEKELESEESLWGLYERWRSHHTVSRSWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQNQGCNGGLMDYAFEF	360	"Experimental evidence at protein level"	40110.92	40085.52	5.98	--NA--	"FUNCTION:Involved in programmed cell death.CATALYTIC ACTIVITY:Pronounced preference for hydrophobic residues in the P2 position and no obvious preference in the P1 position of the cleavage site. Accepts proline at the P1 and P1' positions.ENZYME REGULATION:Low pH triggers activation of the protease and removal of the propeptide and the KDEL motif.DEVELOPMENTAL STAGE:Released during the final stage of cellular desintegration in the senescing endosperm of germinating bean.PTM:The potential N-glycosylation site at Asn-115 is not glycosylated.MISCELLANEOUS:The pro-endopeptidase goes directly from the ER lumen to the ricinosome, and the secretory pathway via the Golgi apparatus is not involved in the ricinosome biogenesis.SIMILARITY:Belongs to the peptidase C1 family."