PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_4359	RETO_ESCCA	--NA--	"Eschscholzia californica"	Papaveraceae	--NA--	Signaling-peptide	"Alkaloid metabolism; Cytoplasmic vesicle; Direct protein sequencing; FAD; Flavoprotein; Glycoprotein; Oxidoreductase; Signal | Reticuline oxidase precursor (EC 1.21.3.3) (Berberine bridge-forming,enzyme) (BBE) (Tetrahydroprotoberberine synthase).Cytoplasmic vesicle."	--NA--	AITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISKTLIDPNNVFNHPQSIPPMANFDYLEKTLGSDGGEVVILKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKMENKTPIFFSLSIFLSLLNCALGGNDLLSCLTFNGVRNHTVFSADSDSDFNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRANRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFG	538	"Experimental evidence at protein level"	59958.31	59920.43	5.27	--NA--	"FUNCTION:Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack.Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.CATALYTIC ACTIVITY:(S)-reticuline O(2) = (S)-scoulerine H(2)O(2).COFACTOR:FAD.COFACTOR:Metal ion.PATHWAY:Alkaloid biosynthesis; (S)-scoulerine biosynthesis; (S)- scoulerine from (S)-reticuline: step 1/1.SIMILARITY:Belongs to the oxygen-dependent FAD-linked oxidoreductase family."