PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_3948	"Viscotoxin-A3 (VtA3)"	"10947973, 5719166, 4941626, 1710983, 15086811"	"Viscum album"	Santalaceae	Thionin	Antifungal	"To control and/or inhibit the growth of phytopathogenic fungi."	"Fungi: Fusarium solani, Sclerotinia sclerotiorum, Phytophtora infestans."	KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK	46	"Experimental evidence at protein level"	4835.6	4832.31	9.3	"NMR, HPLC"	"Mistletoe extracts have immunomodulatory activity by increasing natural killer (NK) cell-mediated killing of tumor cells but spare nontarget cells from NK lysis (Tabiasco et al., 2002). It consists of 3 S-S bonds. The arrangement of the cysteine pairing was determined as Cys3-Cys40, Cys4-Cys32 and Cys16-Cys26. In addition to the NMR structure (link), a crystal structure has also been solved with the same fold (Acta Cryst 2003; D59: 2125-32). You can rotate, zoom, and view the 3D structure here in the PDB. Another six homologs Vt A1, A2, B, C1, 1-PS, and U-PS have been found to date (see subsequent entries). VtA3 is the most cytotoxic while VtB is the least toxic. MOA: antifungi by membrane targeting and forming channels. Updated 2/2014; 8/2015."
